Benzydamine is a non-steroidal anti-inflammatory drug (NSAID) that also exhibits analgesic, anesthetic, and antibacterial activities. Benzydamine is clinically used to treat mucositis and sore throat. Unlike most NSAIDs, benzydamine inhibits prostaglandin synthetase, not cyclooxygenase (COX).
| Cas No. | 132-69-4 |
|---|---|
| Purity | ≥98% |
| Formula | C19H23N3O • HCl |
| Formula Wt. | 345.87 |
| Chemical Name | N,N-Dimethyl-3-[[1-(phenylmethl)-1H-indazol-3-yl]oxy]-1-propanamine hydrochloride |
| IUPAC Name | 3-(1-benzylindazol-3-yl)oxy-N,N-dimethylpropan-1-amine;hydrochloride |
| Synonym | Benzindamine hydrochloride |
| Melting Point | 156-161°C |
| Solubility | Soluble in water, ethanol, chloroform, n-butanol or DMSO |
| Appearance | White to Off-White Crystal Powder |
| Store Temp | Ambient |
|---|---|
| Ship Temp | Ambient |
| MSDS | B1640 MSDS PDF |
|---|---|
| Info Sheet | B1640 Info Sheet PDF |
Chen CY, Kuo CJ, Lee YW, et al. Benzydamine hydrochloride on postoperative sore throat: a meta-analysis of randomized controlled trials. Can J Anaesth. 2014 Mar;61(3):220-8. PMID: 24263969.
Karavana Hizarcioğlu SY, Sezer B, Güneri P, et al. Efficacy of topical benzydamine hydrochloride gel on oral mucosal ulcers: an in vivo animal study. Int J Oral Maxillofac Surg. 2011 Sep;40(9):973-8. PMID: 21549562.
Fanaki NH, el-Nakeeb MA. Antimicrobial activity of benzydamine, a non-steroid anti-inflammatory agent. J Chemother. 1992 Dec;4(6):347-52. PMID: 1287137.
