Besifloxacinisafourthgenerationfluoroquinoloneantibioticthatdisplaysbroad-spectrumantibacterialactivityagainstaerobicandanaerobicbacteriaandiseffectiveagainstawiderangeofocularpathogensthatexhibitresistancetootherfluoroquinoloneantibiotics.BesifloxacininhibitsDNAtopoisomeraseIVandDNAgyrase,preventingDNAreplication,transcription,andrepair.ThiscompoundalsoinhibitsproductionofIL-1Ra,IL-6,IL-1-β,MCP-1,andotherpro-inflammatorycytokines;itmayalsoinhibitNF-kBsignaling.
| CasNo. | 405165-61-9 |
|---|---|
| Purity | ≥98% |
| Formula | C19H22ClFN3O3•HCl |
| FormulaWt. | 430.31 |
| ChemicalName | 7-[(3R)-3-aminoazepam-1-yl]-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylicacidhydrochloride |
| IUPACName | 7-[(3R)-3-aminoazepan-1-yl]-8-chloro-1-cyclopropyl-6-fluoro-4-oxoquinoline-3-carboxylicacid;hydrochloride |
| Solubility | Sparinglysolubleinwater(1mg/mL),DMSO(<1> |
| Appearance | Whitetooff-whitepowder |
| StoreTemp | -20°C |
|---|---|
| ShipTemp | Ambient |
| MSDS | B1973MSDSPDF |
|---|---|
| InfoSheet | B1973InfoSheetPDF |
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