Biapenemisacarbapenemβ-lactamantibiotic.Likeothercarbapenems,biapenembindspenicillin-bindingproteinstoinhibitbacterialcellwallsynthesis.Biapenemexhibitsbroadspectrumantibacterialactivityandisclinicallyusedtotreatrespiratoryandurinarytractinfections.Biapenemdisplaysactivityagainstseveralspeciesofbacteria,includingBacteriodes,Prevotella,Clostridium,andPseudomonas.Inanimalmodelsofpneumonia,biapenemdecreasesbacterianumbersandincreasessurvivalrates.
| CasNo. | 120410-24-4 |
|---|---|
| Purity | ≥98% |
| Formula | C15H18N4O4S |
| FormulaWt. | 350.39 |
| ChemicalName | (4R,5R,6S)-3-(3,5-diaza-1-azoniABIcyclo[3.3.0]octa-1,3-dien-7-ylsulfanyl)-6-(1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate |
| IUPACName | (4R,5S,6S)-3-(6,7-dihydro-5H-pyrazolo[1,2-a][1,2,4]triazol-4-ium-6-ylsulfanyl)-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylicacid |
| Synonym | 6-(((4R,5S,6S)-2-Carboxy-6-((1R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo(3.2.0)hept-2-en-3-yl)thio)-6,7-dihydro-5H-pyrazolo(1,2-a)-s-triazol-4-iumhydroxide,innersalt;L-627;CL-186,815;LJ-C10,627 |
| Appearance | Slightlyyellowpowder |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| MSDS | B3203MSDSPDF |
|---|---|
| InfoSheet | B3203InfoSheetPDF |
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