Description
TenofovirisanantiviralcompoundthatisclinicallyusedtotreathepatitisBandHIV-1infections.Tenofovirisanucleotideanalogandinhibitorofreversetranscriptase.Thiscompoundisalsoindevelopmentasapotentialtreatmentforfelineleukemiavirus(FeLuk).
TenofovirisanantiviralcompoundthatisclinicallyusedtotreathepatitisBandHIV-1infections.Tenofovirisanucleotideanalogandinhibitorofreversetranscriptase.Thiscompoundisalsoindevelopmentasapotentialtreatmentforfelineleukemiavirus(FeLuk).
CasNo. | 206184-49-8 |
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Purity | ≥98% |
Formula | C9H14N5O4P•H2O |
FormulaWt. | 305.23 |
IUPACName | [(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethylphosphonicacid;hydrate |
Appearance | Whitetooffwhitepowder |
StoreTemp | Ambient |
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ShipTemp | Ambient |
MSDS | T1854MSDSPDF |
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InfoSheet | T1854InfoSheetPDF |
Brochures | AntiviralsBooklet |
QiuLP,ChenL,ChenKP.AntihepatitisBtherapy:areviewofcurrentmedicationsandnovelsmallmoleculeinhibitors.FundamClinPharmacol.2013Oct4.[Epubaheadofprint].PMID:24118072.
IyidoganP,AndersonKS.Recentfindingsonthemechanismsinvolvedintenofovirresistance.AntivirChemChemother.2013Jun6.[Epubaheadofprint].PMID:23744599.
GreggsWM3rd,ClouserCL,PattersonSE,etal.Discoveryofdrugsthatpossessactivityagainstfelineleukemiavirus.JGenVirol.2012Apr;93(Pt4):900-5.PMID:22258856.
RohanLC,MonclaBJ,KunjaraNaAyudhyaRP,etal.InvitroandexvivotestingoftenofovirshowsitiseffectiveasanHIV-1microbicide.PLoSOne.2010Feb19;5(2):e9310.PMID:20174579.