LKT/TETRACYCLINE HYDROCHLORIDE/T1679/1 g-免疫在线蚂蚁淘旗下平台

商品详细LKT/TETRACYCLINE HYDROCHLORIDE/T1679/1 g

LKT/TETRACYCLINE HYDROCHLORIDE/T1679/1 g

商品编号： T1679-1g

品牌： lktlabs

市场价： ¥580.00

美元价： 348.00

产地：美国(厂家直采)

公司：

产品分类：临床研究

公司分类： clinical_research

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

ProductIDT1679

CasNo.64-75-5

Purity≥96%

Description
ProductInfo
ShippingandStorage
Downloads
References

Description

TetracyclineisapolyketideantibioticoriginallyproducedbyStreptomycesthatexhibitsantibacterialandneuroprotectiveactivities.Tetracyclinebindsthe30Ssubunitofthebacterialribosome,preventingaminoacyl-tRNAfrombindingtotheribosomalAsiteandinhibitingproteinsynthesis.Tetracyclineisclinicallyusedtotreatacne,rosacea,Lymedisease,andvariousbacterialinfections.Tetracyclinebindsamyloid-β(Aβ)peptides,increasingtheirsolubilityanddecreasingtheirneurotoxicityinvitro.Tetracyclinemayalsoinhibitmatrixmetalloproteinases(MMPs).Additionally,tetracyclineinhibitsmammalianRNAsplicing.

ProductInfo

CasNo.	64-75-5
Purity	≥96%
Formula	C₂₂H₂₄N₂O₈•HCl
FormulaWt.	480.90
ChemicalName	[4S-(4α,4aα,5aα,6β,12aα)]-4-(Dimethylamino)-1,4,4a,5,5a,6-11,12a-octahydro-3,6,10,12,12a-penta-hydroxy-6-methyl-1,11-dioxo-2-naphthacene-carboxamidehydrochloride
IUPACName	(4S,4aS,5aS,6S,12aR)-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide;hydrochloride
Synonym	Achromycin;Panmycin;Topicycline;Cylcopar;Diocyclin
MeltingPoint	220-223°C
Solubility	Solubleinwater(100mg/mL),methanolandethanol(10mg/mL).Insolubleinetherandhydrocarbons.
Appearance	YellowCrystallinePowder

ShippingandStorage

StoreTemp	4°C
ShipTemp	Ambient

Downloads

InfoSheet	T1679InfoSheetPDF

References

KennedyR,AlibhaiM,ShakibK.Tetracycline:acureall?BrJOralMaxillofacSurg.2014Apr;52(4):382-3.PMID:24613100.

MahajanGB,BalachandranL.Antibacterialagentsfromactinomycetes-areview.FrontBiosci(EliteEd).2012Jan1;4:240-53.PMID:22201868.

AiroldiC,ColomboL,ManzoniC,etal.TetracyclinepreventsAβoligomertoxicitythroughanatypicalsupramolecularinteraction.OrgBiomolChem.2011Jan21;9(2):463-72.PMID:21063627.

GriffinMO,FricovskyE,CeballosG,etal.Tetracyclines:apleitropicfamilyofcompoundswithpromisingtherapeuticproperties.Reviewoftheliterature.AmJPhysiolCellPhysiol.2010Sep;299(3):C539-48.PMID:20592239.

HertweckM,HillerR,MuellerMW.Inhibitionofnuclearpre-mRNAsplicingbyantibioticsinvitro.EurJBiochem.2002Jan;269(1):175-83.PMID:11784311.

品牌介绍

LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供：癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的，为全球提供先端的药物研发试剂、试剂盒、委托合成，并为药物生产企业提供原料，最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。试剂