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当前位置: 首页 > 产品中心 > clinical_research > LKT/茶黄素-3-没食子酸酯/T286165/1mg
商品详细LKT/茶黄素-3-没食子酸酯/T286165/1mg
LKT/茶黄素-3-没食子酸酯/T286165/1mg
LKT/茶黄素-3-没食子酸酯/T286165/1mg
商品编号: T286165-1mg
品牌: lktlabs
市场价: ¥2420.00
美元价: 1452.00
产地: 美国(厂家直采)
公司:
产品分类: 临床研究
公司分类: clinical_research
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References

Description

Theaflavin-3-gallate is a polyphenolic compound found in black tea. The theaflavins are formed during the enzymatic oxidation of catechins, which happens during processing of the fresh tea leaves. Theaflavin-3-gallate has been shown to have inhibitory effects on ovarian cancer cells OVCAR-3 and A2780/CP70 by inducing apoptosis and impairing tumor angiogenesis. In addition, theaflavin-3-gallate was found to give stronger reactive oxygen species scavenging activity than theaflavin by a chemiluminescence assay. Exposure of CAL27 and HSC-2 carcinoma cells to theaflavin-3-gallate demostrated cytotoxic and antiproliferative properties of the compound.

Product Info

Cas No.

30462-34-1

Purity

≥95%

Formula

C36H28O16

Formula Wt.

716.60

IUPAC Name

(2R,3R)-5,7-Dihydroxy-2-{3,4,5-trihydroxy-6-oxo-1-[(2R,3R)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-2-yl]-6H-benzo[7]annulen-8-yl}-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate

Shipping and Storage

Store Temp

4°C

Downloads

Info Sheet

T286165 Info Sheet PDF

References

Gao Y, Rankin GO, Tu Y, et al. Inhibitory effects of the four main theaflavin derivatives found in black tea on ovarian cancer cells. Anticancer Res. 2016 Feb;36(2):643-651. PMID: 26851019.

Wu YY, Li W, Xu Y, et al. Evaluation of the antioxidant effects of four main theaflavin derivatives through chemiluminescence adn DNA damage analyses. J Zhejiang Univ Sci B. 2011 Sep;12(9):744-751. PMID: 21887850.

Babich H, Gottesman RT, Liebling EJ, et al. Theaflavin-3-gallate and theaflavin-3’-gallate, polyphenols in black tea with prooxidant properties. Basic Clin Pharmacol Toxicol. 2008 Jul;103(1):66-74. PMID: 18346048.

品牌介绍
LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。 试剂