Thiabendazoleisabenzimidazoleantifungalthatexhibitsadditionalantibioticactivityaswellasanticancerchemotherapeuticandanti-angiogenicactivities.Thiabendazolebindstubulinandactsasaspindlepoison,alteringmicrotubulepolymerizationandinhibitinggrowthofAspergillus.ThiabendazolealsodisplaysnematocidalactivityagainstStrongyloidesandanti-helminthicactivityagainstHaemonchus.Thiscompoundinhibitsproliferation,angiogenesis,andVEGFexpressioninmelanomacellsandpreventstumorgrowthinvivo.
| CasNo. | 148-79-8 |
|---|---|
| Purity | ≥98% |
| Formula | C10H7N3S |
| FormulaWt. | 201.25 |
| ChemicalName | 2-(4-Thiazolyl)-1H-benzimidazole |
| IUPACName | 4-(1H-benzimidazol-2-yl)-1,3-thiazole |
| Synonym | MK-360;Thibenzole;Equizole;Mertect;Storite;TBZ;Tecto. |
| MeltingPoint | 300-303°C |
| Solubility | SolubleinDMFandDMSO.Slightlysolubleinalcoholsandesters. |
| Appearance | Whitetooffwhitepowder |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| MSDS | T2930MSDSPDF |
|---|---|
| InfoSheet | T2930InfoSheetPDF |
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