Description
Tioconazole is an imidazole antifungal and antibacterial compound that damages cell membranes. Tioconazole is most active against fungi, molds, and gram positive bacteria.
Tioconazole is an imidazole antifungal and antibacterial compound that damages cell membranes. Tioconazole is most active against fungi, molds, and gram positive bacteria.
Cas No. | 65899-73-2 |
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Purity | ≥98% |
Formula | C16H13Cl3N2OS |
Formula Wt. | 387.71 |
Chemical Name | 1-[2-[(2-Chloro-3-thienyl)methoxy]-2-(2,4- dichlorophenyl)ethyl]-1H-imidazole |
IUPAC Name | 1-[2-[(2-chlorothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl]imidazole |
Synonym | Vagistat; Fungibacid; Trosyd; Zoniden |
Melting Point | 168-170°C |
Solubility | Moderately soluble in chloroform, ethanol, methanol or ethyl acetate. |
Appearance | White or almost white crystalline powder |
Store Temp | Ambient |
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Ship Temp | Ambient |
Info Sheet | T3357 Info Sheet PDF |
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Jones RN, Bale MJ, Hoban D, et al. In vitro antimicrobial activity of tioconazole and its concentrations in vaginal fluids following topical (vagistat-1 6.5%) application. Diagn Microbiol Infect Dis. 1993 Jul;17(1):45-51. PMID: 8359005.
Odds FC, Cheesman SL, Abbott AB. Suppression of ATP in Candida albicans by imidazole and derivative antifungal agents. Sabouraudia. 1985 Dec;23(6):415-24. PMID: 3913012.