ADX47273isapositiveallostericmodulatorofmetabotropicglutamatereceptormGluR5thatdisplaysantipsychotic,neuromodulatory,andcognitionenhancingactivities.Invivo,ADX47273increaseswakinganddecreasesdeepsleepbehaviors;italsoincreaseslatephaselong-termpotentiation(LTP)andenhancesadaptivelearning.Inotheranimalmodels,ADX47273decreasesamphetamine-andphencyclidine-inducedhyperlocomotionandaccumbaldopaminelevels.
| CasNo. | 851881-60-2 |
|---|---|
| Purity | ≥98% |
| Formula | C20H17F2N3O2 |
| FormulaWt. | 369.36 |
| StoreTemp | -20°C |
|---|---|
| ShipTemp | Ambient |
| InfoSheet | A1592InfoSheetPDF |
|---|
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