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当前位置: 首页 > 产品中心 > clinical_research > LKT/AGOMELATINE/A2658/100 mg
商品详细LKT/AGOMELATINE/A2658/100 mg
LKT/AGOMELATINE/A2658/100 mg
LKT/AGOMELATINE/A2658/100 mg
商品编号: A2658-100mg
品牌: lktlabs
市场价: ¥2140.00
美元价: 1284.00
产地: 美国(厂家直采)
公司:
产品分类: 临床研究
公司分类: clinical_research
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References

Description

Agomelatine is a melatonin MT1/2 receptor activator that also inhibits 5-HT2C receptors. Agomelatine displays antidepressant, anxiolytic, and hypnotic characteristics and is currently being examined as a marketable antidepressant. Agomelatine improves sleep quality and efficacy and treats insomnia. This compound also enhances neuroplasticity and neurogenesis in the hippocampus and prefrontal cortex.

Product Info

Cas No.

138112-76-2

Purity

≥98%

Formula

C15H17NO2

Formula Wt.

243.30

IUPAC Name

N-[2-(7-methoxynaphthalen-1-yl)ethyl]acetamide

Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

A2658 MSDS PDF

Info Sheet

A2658 Info Sheet PDF

References

Smeraldi E, Delmonte D. Agomelatine in depression. Expert Opin Drug Saf. 2013 Nov;12(6):873-80. PMID: 24033095.

Pompili M, Serafini G, Innamorati M, et al. Agomelatine, a novel intriguing antidepressant option enhancing neuroplasticity: a critical review. World J Biol Psychiatry. 2013 Aug;14(6):412-31. PMID: 23530731.

Srinivasan V, Zakaria R, Othaman Z, et al. Melatonergic drugs for therapeutic use in insomnia and sleep disturbances of mood disorders. CNS Neurol Disord Drug Targets. 2012 Mar;11(2):180-9. PMID: 22483286.

Bertaina-Anglade V, la Rochelle CD, Boyer PA, et al. Antidepressant-like effects of agomelatine (S 20098) in the learned helplessness model. Behav Pharmacol. 2006 Dec;17(8):703-13. PMID: 17110796.

Papp M, Litwa E, Gruca P, et al. Anxiolytic-like activity of agomelatine and melatonin in three animal models of anxiety. Behav Pharmacol. 2006 Feb;17(1):9-18. PMID: 16377959.

品牌介绍
LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。 试剂