Ampiroxicamisanon-steroidalanti-inflammatorydrug(NSAID)thatexhibitsanti-inflammatoryandanalgesicactivities;itinhibitsCOX-1andCOX-2.Ampiroxicamisaprodrugofpiroxicamthatdoesnotinhibitprostaglandinsynthesisitself.Inanimalmodelsofinflammation,ampiroxicamdecreasespawedema.
| CasNo. | 99464-64-9 |
|---|---|
| Purity | ≥98% |
| Formula | C20H21N3O7S |
| FormulaWt. | 447.46 |
| ChemicalName | Carbonicacidethyl1-[[2-methyl-3-[(2-pyridinyl-amino)carbonyl]-2H-1,2-benzothiazin-4-yl]oxy]ethylesterS,S-dioxide |
| IUPACName | ethyl1-[[2-methyl-1,1-dioxo-3-(pyridin-2-ylcarbamoyl)-1λ6,2-benzothiazin-4-yl]oxy]ethylcarbonate |
| Synonym | CP-65703;Flucam |
| MeltingPoint | 159-161°C |
| Solubility | Solubleinalcohol.Insolubleinacetone. |
| Appearance | WhiteCrystallinePowder,AlmostOdorless |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| InfoSheet | A5161InfoSheetPDF |
|---|
SaiS,FujiiK,HiranumaK,etal.Preoperativeampiroxicamreducespostoperativepainafterhandsurgery.JHandSurgBr.2001Aug;26(4):377-9.PMID:11469844.
CartyTJ,MarfatA,MoorePF,etal.Ampiroxicam,ananti-inflammatoryagentwhichisaprodrugofpiroxicam.AgentsActions.1993Jul;39(3-4):157-65.PMID:8304243.
