Anabaenopeptins are cyclopentapeptides found in cyanobacteria such as Microcystis aeruginosa and Oscillatoria agardhii. Anabaenopeptins and other cyanotoxins are typically inhibitors of serine proteases and protein phosphatases (PPs). Anabaenopeptins may also inhibit carboxypeptidases. Anabaenopeptins B and F are considered “nontoxic” compared to other variants.
| Cas No. | 161897-74-1 |
|---|---|
| Purity | ≥95% |
| Formula | C41H60N10O9 |
| Formula Wt. | 836.98 |
| IUPAC Name | (2S)-2-[[(3S,6S,9S,12S,15R)-3-benzyl-9-[2-(4-hydroxyphenyl)ethyl]-6,7-dimethyl-2,5,8,11,14-pentaoxo-12-propan-2-yl-1,4,7,10,13-pentazacyclononadec-15-yl]carbamoylamino]-5-(diaminomethylideneamino)pentanoic acid |
| Appearance | White Film |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Blue Ice |
| Info Sheet | A5201 Info Sheet PDF |
|---|
Gesner-Apter S, Carmeli S. Protease inhibitors from a water bloom of the cyanobacterium Microcystis aeruginosa. J Nat Prod. 2009 Aug;72(8):1429-36. PMID: 19650639.
Okumura HS, Philmus B, Portmann C, et al. Homotyrosine-containing cyanopeptolins 880 and 960 and anabaenopeptins 908 and 915 from Planktothrix agardhii CYA 126/8. J Nat Prod. 2009 Jan;72(1):172-6. PMID: 19115837.
Sedmak B, Carmeli S, Elersek T. "Non-toxic" cyclic peptides induce lysis of cyanobacteria-an effective cell population density control mechanism in cyanobacterial blooms. Microb Ecol. 2008 Aug;56(2):201-9. PMID: 18008101.
Itou Y, Suzuki S, Ishida K, et al. Anabaenopeptins G and H, potent carboxypeptidase A inhibitors from the cyanobacterium Oscillatoria agardhii (NIES-595). Bioorg Med Chem Lett. 1999 May 3;9(9):1243-6. PMID: 10340607.
