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当前位置: 首页 > 产品中心 > clinical_research > LKT/ANIRACETAM/A5326/100 mg
商品详细LKT/ANIRACETAM/A5326/100 mg
LKT/ANIRACETAM/A5326/100 mg
LKT/ANIRACETAM/A5326/100 mg
商品编号: A5326-100mg
品牌: lktlabs
市场价: ¥2300.00
美元价: 1380.00
产地: 美国(厂家直采)
公司:
产品分类: 临床研究
公司分类: clinical_research
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
  • Description
  • ProductInfo
  • ShippingandStorage
  • Downloads
  • References

Description

Aniracetamisanootropicampakinethatexhibitsanxiolyticandneuroprotectiveactivities.AniracetamactsasapositiveallostericmodulatorofAMPAreceptors,slowingreceptordeactivation;italsoactsonD2receptors,5-HT2Areceptors,andnicotinicacetylcholinereceptors(nAChRs),likelydisplayingagoNISTactivity.Aniracetamdecreasesanxietyinvivointheconditionfearstresstest,elevatedplusmazetest,andinsocialinteractiontests.Additionally,thiscompoundinhibitsH2O2-induceddeficitsinlong-termpotentiationandneuronviABIlity.AniracetamshowssomeclinicalbenefitintheenhancementofcognitivedeficitsassociatedwithstrokeandAlzheimer’sdisease.

ProductInfo

CasNo.

72432-10-1

Purity

≥98%

Formula

C12H13NO3

FormulaWt.

219.24

ChemicalName

1-(4-Methoxybenzoyl)-2-pyrrolidinone

IUPACName

1-(4-methoxybenzoyl)pyrrolidin-2-one

Synonym

Ro-13-5057;Draganon;Sarpul 

MeltingPoint

121-122°C

Solubility

Solubleinchloroformandethylacetate.Slightlysolubleinethanol.Insolubleinwater.

Appearance

WhiteoralmostWhiteCrystallinePowder

ShippingandStorage

StoreTemp

Ambient

ShipTemp

Ambient

Downloads

InfoSheet

A5326InfoSheetPDF

References

WangYF,LiCC,CaiJX.AniracetamattenuatesH2O2-induceddeficiencyofneuronviability,mitochondriapotentialandhippocampallong-termpotentiationofmiceinvitro.NeurosciBull.2006Sep;22(5):274-80.PMID:17690727.

JinR,ClarkS,WeeksAM,etal.MechanismofpositiveallostericmodulatorsactingonAMPAreceptors.JNeurosci.2005Sep28;25(39):9027-36.PMID:16192394.

NakamuraK.Aniracetam:itsnoveltherapeuticpotentialincerebraldysfunctionaldisordersbasedonrecentpharmacologicaldiscoveries.CNSDrugRev.2002Spring;8(1):70-89.PMID:12070527.

NakamuraK,KurasawaM.Anxiolyticeffectsofaniracetaminthreedifferentmousemodelsofanxietyandtheunderlyingmechanism.EurJPharmacol.2001May18;420(1):33-43.PMID:11412837.

ItoI,TanabeS,KohdaA,etal.Allostericpotentiationofquisqualatereceptorsbyanootropicdruganiracetam.JPhysiol.1990May;424:533-43.PMID:1975272.

品牌介绍
LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。 试剂