Vilazodoneisanantidepressantthatalsoexhibitssomeanxiolyticefficacyinanimalmodels.VilazodoneinhibitstheSEROtonintransporter(SERT),preventingserotoninreuptake,andalsoactsasapartialagoNISTatthe5-HT1Areceptor;thiscompoundhasnegligIBLeactivityatother5-HTreceptorsoronNETsandDATs.Unlikemanyotherantidepressants,vilazodonedoesnotexhibitanypotentiallyharmfulcardiaceffects.
| CasNo. | 163521-12-8 |
|---|---|
| Purity | ≥98% |
| Formula | C26H27N5O2 |
| FormulaWt. | 441.52 |
| IUPACName | 5-[4-[4-(5-cyano-1H-indol-3-yl)butyl]piperazin-1-yl]-1-benzofuran-2-carboxamide |
| MeltingPoint | 203-205°C |
| Appearance | LightTanpowder |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| InfoSheet | V3444InfoSheetPDF |
|---|
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TreitD,DegrootA,kashlubaS,etal.SystemicEMD68843injectionsreduceanxietyintheshock-probe,butnottheplus-mazetest.EurJPharmacol.2001Mar2;414(2-3):245-8.PMID:11239925.
