ZiprasidoneisanatypicalantipsychoticthatactsasanantagoNISTatD2receptorsand5-HT1Dreceptorsandasanagonistat5-HT1Areceptors;thisbindingprofileallowsittoexhibitantipsychotic,antidepressant,andanxiolyticbenefits.Ziprasidoneisclinicallyusedtotreatbipolardisorder,schizophrenia,andsleeplessness/insomniainindividualswithpsychosis.Inaclinicalsetting,ziprasidoneimprovedlatencytoREM,durationofslowwavesleep,totalsleeptime,andsleepefficiency.
| CasNo. | 146939-27-7 |
|---|---|
| Purity | ≥98% |
| Formula | C21H21ClN4OS |
| FormulaWt. | 412.94 |
| ChemicalName | 2H-Indol-2-one,5-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinyl)ethyl)-6-chloro-1,3-dihydro- |
| IUPACName | 5-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]-6-chloro-1,3-dihydroindol-2-one |
| Synonym | Geodon,Zeldox |
| MeltingPoint | 213-215°C |
| Appearance | Palebrownpowder |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| InfoSheet | Z3463InfoSheetPDF |
|---|
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FindlingRL,CavuşI,PappadopulosE,etal.Efficacy,long-termsafety,andtolerABIlityofziprasidoneinchildrenandadolescentswithbipolardisorder.JChildAdolescPsychopharmacol.2013Oct;23(8):545-57.PMID:24111980.
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