γ-Aminobutyric acid (GABA) is an endogenous neurotransmitter that controls neuronal excitability, muscle tone, stem cell growth, brain development, and mood. During development, GABA acts as an excitatory neurotransmitter but switches later to an inhibitory function. GABA displays anxiolytic, anticonvulsant, and amnestic activities, inducing relaxation and decreasing anxiety in clinical settings.
| Cas No. | 56-12-2 |
|---|---|
| Purity | ≥98% |
| Formula | C4H9NO2 |
| Formula Wt. | 103.12 |
| Chemical Name | 4-Aminobutanoic acid |
| IUPAC Name | 4-aminobutanoic acid |
| Synonym | γ-Aminobutyric acid; Gammalon; GABA; gamma-amino butyric acid |
| Melting Point | 202°C(dec) |
| Solubility | Soluble in water. Practically insoluble in other solvents. |
| Appearance | White-almost white crystalline powder |
| Store Temp | Ambient |
|---|---|
| Ship Temp | Ambient |
| MSDS | G0048 MSDS PDF |
|---|---|
| Info Sheet | G0048 Info Sheet PDF |
Li K, Xu E. The role and the mechanism of gamma-aminobutyric acid during central nervous system development. Neurosci Bull. 2008 Jun;24(3):195-200. PMID: 18500393.
Abdou AM, Higashiguchi S, Horie K, et al. Relaxation and immunity enhancement effects of gamma-aminobutyric acid (GABA) administration in humans. Biofactors. 2006;26(3):201-8. PMID: 16971751.
Foster AC, Kemp JA. Glutamate- and GABA-based CNS therapeutics. Curr Opin Pharmacol. 2006 Feb;6(1):7-17. PMID: 16377242.
