Description
AngiotensinIII(ATIII)isthesmallest,leastactivepeptidefragmentofprecursorangiotensinogen.ATIIIisanendogenouspeptideproducedbythedegradationofATIIbyangiotensinase.ATIIIhas40%ofthevasoconstrictivepressoractivityofATIIbutincreasesaldosteronesecretionandmeanarterialpressurethroughactivityattheATIItype1(AT1)receptor.
References
YugandharVG,ClarkMA.AngiotensinIII:aphysiologicalrelevantpeptideofthereninangiotensinsystem.Peptides.2013Aug;46:26-32.PMID:23692861.
YangR,SmoldersI,DupontAG.Bloodpressureandrenalhemodynamiceffectsofangiotensinfragments.HypertensRes.2011Jun;34(6):674-83.PMID:21412242.
DupontAG,BrouwersS.Brainangiotensinpeptidesregulatesympathetictoneandbloodpressure.JHypertens.2010Aug;28(8):1599-610.PMID:20502352.