Tuftsinisatetrapeptidethatbindstheneuropilin-1(Nrp1)receptor,modulatingTGF-β,cGMP,andCa2+signaling.TuftsinisderivedfromtheFcregionofIgG.Tuftsinexhibitsimmunomodulatoryactivity,inducingleukocytestobecomecytotoxiceffectorcellsandstimulatingphagocytosisinmacrophagesandmicrogliaincellularmodels.Tuftsinalsodisplaysanticancerchemotherapeuticbenefit,enhancingtheeffectsofco-admiNISTeredchemotherapeuticcompounds.Inanimalmodels,tuftsinalsoinhibitswithdrawal-associatedbehaviors.
| CasNo. | 9063-57-4 |
|---|---|
| Purity | ≥95% |
| Formula | C21H40N8O6 |
| FormulaWt. | 500.6 |
| IUPACName | (2S)-2-[[(2S)-1-[6-amino-2-[[(2S,3R)-2-amino-3-hydroxybutanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoicacid |
| Appearance | Whitetooffwhitepowder |
| StoreTemp | -20°C |
|---|---|
| ShipTemp | Ambient |
| MSDS | T8020MSDSPDF |
|---|---|
| InfoSheet | T8020InfoSheetPDF |
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