Urodilatin is a natriuretic and diuretic peptide fragment of atrial natriuretic peptide (ANP). Urodilatin regulates Na+ and water transport across renal proximal tubules through inhibition of the Na+/K+ ATPase. Urodilatin increases renal dopamine uptake and also increases cGMP/PKG activity.
| Cas No. | 115966-23-9 |
|---|---|
| Purity | ≥98% |
| Formula | C145H234N52O44S3 |
| Formula Wt. | 3506.0 |
| Synonym | Ularitide; Atriopeptin; Anp; Anf; ANP (95-129); A-type natriuretic peptide; Atrial natriuretic peptide |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| Info Sheet | U6857 Info Sheet PDF |
|---|
Choi MR, Citarella MR, Lee BM, et al. Urodilatin regulates renal dopamine metabolism. J Nephrol. 2013 Nov-Dec;26(6):1042-8. PMID: 23661592.
Vives D, Farage S, Motta R, et al. Atrial natriuretic peptides and urodilatin modulate proximal tubule Na(+)-ATPase activity through activation of the NPR-A/cGMP/PKG pathway. Peptides. 2010 May;31(5):903-8. PMID: 20206222.
