Description
CASIN is an inhibitor of the Cdc42 GTPase; it may exhibit neuroprotective activity by stimulating the rejuvenation of aged hematopoietic stem cells.
CASIN is an inhibitor of the Cdc42 GTPase; it may exhibit neuroprotective activity by stimulating the rejuvenation of aged hematopoietic stem cells.
Cas No. | 425399-05-9 |
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Purity | ≥98% |
Formula | C20H22N2O |
Formula Wt. | 306.41 |
IUPAC Name | 2-[(6-Phenyl-2,3,4,9-tetrahydro-1H-carbazol-1-yl)amino]ethanol |
Store Temp | -20°C |
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Ship Temp | Ambient |
Info Sheet | C0273 Info Sheet PDF |
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Florian MC, Dörr K, Niebel A, et al. Cdc42 activity regulates hematopoietic stem cell aging and rejuvenation. Cell Stem Cell. 2012 May 4;10(5):520-30. PMID: 22560076.
Peterson JR, Lebensohn AM, Pelish HE, et al. Biochemical suppression of small-molecule inhibitors: a strategy to identify inhibitor targets and signaling pathway components. Chem Biol. 2006 Apr;13(4):443-52. PMID: 16632257.