ChaetoglobosinAisacytochalasantypealkaloidwithpotentantifungalactivityagainstRhizopusstoloniferandConiothyriumdiplodiella.ItisasecondarymetaboliteproducedbytheendophyticfungusChaetomiumglobosumNo.04.Cytochalasansareknowntoexhibitstrongcytotoxicityonvarioushumancancercelllines.
| CasNo. | 50335-03-0 |
|---|---|
| Purity | ≥99% |
| Formula | C32H36N2O5 |
| FormulaWt. | 528.64 |
| ChemicalName | (1E,4S,5E,7R,9E,11aR,14S,14aR,15S,15aR,16aS,16bR)-7-Hydroxy-14-(1H-indol-3-ylmethyl)-4,6,15,15a-tetramethyl-4,7,14,14a,15,15a,16a,16b-octahydro-3H-cyclotrideca[d]oxireno[f]isoindole-8,11,12(13H)-trione |
| IUPACName | (1E,4S,5E,7R,9E,11aR,14S,14aR,15S,15aR,16aS,16bR)-7-Hydroxy-14-(1H-indol-3-ylmethyl)-4,6,15,15a-tetramethyl-4,7,14,14a,15,15a,16a,16b-octahydro-3H-cyclotrideca[d]oxireno[f]isoindole-8,11,12(13H)-trione |
| MeltingPoint | 168-170°C |
| Solubility | SolubleinDMSO,ethanol,methanol. |
| Appearance | Yellowpowder |
| StoreTemp | -20°C |
|---|---|
| ShipTemp | Ambient |
| InfoSheet | C2801InfoSheetPDF |
|---|
ZhangG,ZhangY,QinJ,etal.AntifungalmetabolitesproducedbyChaeyomiumglobosumNo.04,anendophyticfungusisolatedfromGinkobiloba.IndianJMicrobiol.2013Jun;53(2):175-180.PMID:24426105.
