HPGDSInhibitor1isaninhibitorofhematopoieticprostaglandinDsynthase(HPGDS)thatdecreasesreleaseofPGD2.HPGDSInhibitor1displaysanti-inflammatory,anti-allergic,andimmunomodulatoryactivities,decreasingantigen-inducedimmuneandinflammationresponsesinanimalmodels.
| CasNo. | 1033836-12-2 |
|---|---|
| Purity | ≥98% |
| Formula | C19H19F4N3O |
| FormulaWt. | 381.37 |
| IUPACName | 6-(3-Fluorophenyl)-N-[1-(2,2,2-trifluoroethyl)-4-piperidinyl]nicotinamide |
| Synonym | ProstaglandinDSynthase(hematopoietic-type)InhibitorI |
| StoreTemp | -20°C |
|---|---|
| ShipTemp | Ambient |
| InfoSheet | H6225InfoSheetPDF |
|---|
CarronCP,TrujilloJI,OlsonKL,etal.DiscoveryofanOralPotentSelectiveInhibitorofHematopoieticProstaglandinDSynthase(HPGDS).ACSMedChemLett.2010Feb2;1(2):59-63.PMID:24900177.
