Isoindigoinhibitsproliferationinvariousleukemiaandcancercelllines,displayinganticanceractivity.Isoindigoanditsderivativesmayalsobindthearylhydrocarbonreceptor(AhR).Additionally,similarcompoundsshowchemotherapeuticbenefitsinanimalmodelsofleukemia.
| CasNo. | 476-34-6 |
|---|---|
| Purity | ≥98% |
| Formula | C16H10N2O2 |
| FormulaWt. | 262.27 |
| IUPACName | (3E)-3-(2-Oxo-1,2-dihydro-3H-indol-3-ylidene)-1,3-dihydro-2H-indol-2-one |
| Synonym | Isoindigotin |
| StoreTemp | -20°C |
|---|---|
| ShipTemp | Ambient |
| InfoSheet | I7155InfoSheetPDF |
|---|
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BouchikhiF,AnizonF,MoreauP.Synthesisandantiproliferativeactivitiesofisoindigoandazaisoindigoderivatives.EurJMedChem.2008Apr;43(4):755-62.PMID:17628214.
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