Description
R-Sulforaphaneisanaturally-occurringisothiocyanatefoundinbroccoli.Thiscompoundexhibitsantioxidative,anticancer,andchemopreventiveactivities;researchsuggeststhatitmaybemorebioactivethantheS-isomer.R-SulforaphaneincreasesexpressionofphaseIIenzymessuchasglutathione-S-transferaseandquinonereductase;italsoincreasesactivityandexpressionofglucuronosyltransferaseandepoxidehydrolase.Atlowdoses,R-sulforaphanepromotesproliferationofstemcellsandhematopoiesis.Thiscompoundalsoinhibitsthearylhydrocarbonreceptor.Pleasenote:Thiscompoundisaneatliquidatroomtemperature,cleartoslightlyyellowincolor.Itisnotdissolvedinsolvent.InsmallquantitiesthematerialwillcoatthesidesoftheampuleitisshippedinandmayappeartobeinvisIBLe,oritmaybetrappedinthetipoftheampoule.Washtheupperandlowerpartsoftheampoulewithsolventtoensureallofthematerialisobtained.
References
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AbdullRazisAF,BagattaM,DeNicolaGR,etal.Inductionofepoxidehydrolaseandglucuronosyltransferasebyisothiocyanatesandintactglucosinolatesinprecision-cutratliverslices:importanceofside-chainsubstituentandchirality.ArchToxicol.2011Aug;85(8):919-27.PMID:21132492.
AbdullRazisAF,IoriR,IoannidesC.ThenaturalchemopreventivephytochemicalR-sulforaphaneisafarmorepotentinducerofthecarcinogen-detoxifyingenzymesystemsinratliverandlungthantheS-isomer.IntJCancer.2011Jun15;128(12):2775-82.PMID:20726001.
