Description
Rolipramisknowntobeanantidepressantandanxiolytic-likeagentthathasbeenfoundtostimulateangiogenesisandattentuateneuronalapoptosisinischemicrats.
Rolipramisknowntobeanantidepressantandanxiolytic-likeagentthathasbeenfoundtostimulateangiogenesisandattentuateneuronalapoptosisinischemicrats.
CasNo. | 61413-54-5 |
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Purity | ≥98% |
Formula | C16H21NO3 |
FormulaWt. | 275.35 |
IUPACName | 4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone |
Synonym | ZK62711 |
MeltingPoint | 128-129°C |
Solubility | SolubleinDMSO(warm25mg/ml),ethanol(25mg/mlwarm). |
Appearance | Whitetooff-whitepowder |
StoreTemp | Ambient |
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ShipTemp | Ambient |
InfoSheet | R5745InfoSheetPDF |
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HuS,CaoQ,XuP,etal.RolipramstimulatesangiogensisandattenuatesneuronalapoptosisthroughthecAMP/cAMP-responsiveelementbindingproteinpathwayfollowingischemicstrokeinrats.ExpTherMed.2016Mar;11(3):1005-1010.PMID:26998028.
LiYF,HuangY,AMSDellS,etal.Antidepressant-andanxiolytic-likeeffectsofthephosphodiesterase-4inhibitorrolipramonbehaviordependoncyclicAMPresponseelementbindingprotein-mediatedneurogenesisinthehippocampus.Neuropsychopharmacology.2009Oct;34(11):2404-2419.PMID:19516250.