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当前位置: 首页 > 产品中心 > clinical_research > LKT/ALTERNARIOL-9-METHYL ETHER/A4678/5 mg
商品详细LKT/ALTERNARIOL-9-METHYL ETHER/A4678/5 mg
LKT/ALTERNARIOL-9-METHYL ETHER/A4678/5 mg
LKT/ALTERNARIOL-9-METHYL ETHER/A4678/5 mg
商品编号: A4678-5mg
品牌: lktlabs
市场价: ¥18740.00
美元价: 11244.00
产地: 美国(厂家直采)
公司:
产品分类: 临床研究
公司分类: clinical_research
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
  • Description
  • ProductInfo
  • ShippingandStorage
  • Downloads
  • References

Description

Alternariol9-methylether(A9ME)isahighlytoxicmutagenicphytotoxininitiallyproducedbyspeciesofAlternaria.A9MEispresentingrainandfruitusedforlivestockfeedandhumanconsumption.A9MEinhibitstheelectrontransportchain,preventingphotosynthesisinvitro.Additionally,A9MEmayexhibitanticancerpotentialinacellularmodelofcoloncarcinoma,asitdecreasesthemitochondrialmembranepotential,increasingreleaseofcytochromecandactivatingcaspases3and9;thisresultsinapoptosisandcelldeath.

ProductInfo

CasNo.

23452-05-3

Purity

≥98%

Formula

C15H12O5

FormulaWt.

272.25

ChemicalName

6H-Dibenzo(b,d)pyran-6-one,3,7-dihydroxy-9-methoxy-1-methyl

IUPACName

3,7-dihydroxy-9-methoxy-1-methylbenzo[c]chromen-6-one

Solubility

SolubleinDMSO,ethanol,methanol

Appearance

BeigePowder

ShippingandStorage

StoreTemp

4°C

ShipTemp

Ambient

Downloads

InfoSheet

A4678InfoSheetPDF

References

DemunerAJ,BarbosaLC,MirandaAC,etal.TheFungalPhytotoxinAlternariol9-MethylEtherandSomeofItsSyntheticAnaloguesInhibitthePhotosyntheticElectronTransportChain.JNatProd.2013Nov18.[Epubaheadofprint].PMID:24245962.

BroggiL,ReynosoC,ResnikS,etal.OccurrenceofalternariolandalternariolmonomethyletherinbeveragesfromtheEntreRiosProvincemarket,Argentina.MycotoxinRes.2013Feb;29(1):17-22.PMID:23334721.

ScottPM,ZhaoW,FengS,etal.AlternariatoxinsalternariolandalternariolmonomethyletheringrainfoodsinCanada.MycotoxinRes.2012Nov;28(4):261-6.PMID:23087499.

BensassiF,GallerneC,elDeinOS,etal.MechanismofAlternariolmonomethylether-inducedmitochondrialapoptosisinhumancoloncarcinomacells.Toxicology.2011Dec18;290(2-3):230-40.PMID:22001388.

品牌介绍
LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。 试剂