LKT/芹菜素/A6234/100 mg-免疫在线蚂蚁淘旗下平台

商品详细LKT/芹菜素/A6234/100 mg

LKT/芹菜素/A6234/100 mg

商品编号： A6234-100mg

品牌： lktlabs

市场价： ¥3600.00

美元价： 2160.00

产地：美国(厂家直采)

公司：

产品分类：临床研究

公司分类： clinical_research

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

ProductIDA6234

CasNo.520-36-5

Purity≥98%

Description
ProductInfo
ShippingandStorage
Downloads
References

Description

Apigeninisaflavonoidfoundinvariousplantsourcesthatexhibitsanticancer,antioxidative,anti-inflammatory,cognitionenhancing,andneuroprotectiveactivities.Ingastriccancercells,apigenininhibitscellproliferation,decreasesmitochondrialmembranepotential,increasesexpressionofcaspase3andBax,anddecreasesexpressionofBcl-2,inducingapoptosis.Apigeninalsoinducesmicrotubuledepolymerizationinlungcancercells.Additionally,apigenindisplayssomechemopreventivepotential.Inaorticrings,apigenininhibitsvascularcontraction.Inanimalmodelsofspinalcordinjury,apigeninreversesinjury-induceddecreasesinsuperoxidedismutase(SOD)andglutathioneperoxidaseactivityaswellasincreasesinmalondialdehyde;italsodecreasesexpressionofIL-1β,TNF-α,andICAM-1.InanimalmodelsofAlzheimer’sdisease,apigeninsuppressesoxidativestressanddecreaseslevelsofinsolubleamyloid-β(Aβ),amelioratinglearningandcognitivedeficits.Additionally,thiscompoundactsasapositiveallostericmodulatoratGABA-Areceptors.

ProductInfo

CasNo.	520-36-5
Purity	≥98%
Formula	C₁₅H₁₀O₅
FormulaWt.	270.24
ChemicalName	5,7-dihydroxy-2-(4-hydroxyphenyl)-(9CI)-4H-1-Benzopyran-4-one
IUPACName	5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one
Synonym	Apigenine;Apigenol;Chamomile;Spigenin;Versulin
MeltingPoint	345-350°C
Solubility	Moderatelysolubleinhotalcohol.SolubleindiluteKOH.
Appearance	Light-YellowPowder

ShippingandStorage

StoreTemp	Ambient
ShipTemp	Ambient

Downloads

MSDS	A6234MSDSPDF
InfoSheet	A6234InfoSheetPDF

References

ChenJ,ChenJ,LiZ,etal.Theapoptoticeffectofapigeninonhumangastriccarcinomacellsthroughmitochondrialsignalpathway.TumourBiol.2014May8.[Epubaheadofprint].PMID:24805829.

ZhangF,LiF,ChenG.Neuroprotectiveeffectofapigenininratsaftercontusivespinalcordinjury.NeurolSci.2014Apr;35(4):583-8.PMID:24166720.

JeHD,KimHD,LaHO.TheInhibitoryEffectofApigeninontheAgoNIST-InducedRegulationofVascularContractilityviaCalciumDesensitization-RelatedPathways.BiomolTher(Seoul).2014Feb;22(2):100-5.PMID:24753814.

ZhaoL,WangJL,LiuR,etal.Neuroprotective,anti-amyloidogenicandneurotrophiceffectsofapigenininanAlzheimer"sdiseasemousemodel.Molecules.2013Aug19;18(8):9949-65.PMID:23966081.

ChoudhuryD,GanguliA,DastidarDG,etal.Apigeninshowssynergisticanticanceractivitywithcurcuminbybindingatdifferentsitesoftubulin.Biochimie.2013Jun;95(6):1297-309.PMID:23485682.

品牌介绍

LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供：癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的，为全球提供先端的药物研发试剂、试剂盒、委托合成，并为药物生产企业提供原料，最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。试剂