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当前位置: 首页 > 产品中心 > clinical_research > LKT/托瑞米芬碱/T5769/500 mg
商品详细LKT/托瑞米芬碱/T5769/500 mg
LKT/托瑞米芬碱/T5769/500 mg
LKT/托瑞米芬碱/T5769/500 mg
商品编号: T5769-500mg
品牌: lktlabs
市场价: ¥1580.00
美元价: 948.00
产地: 美国(厂家直采)
公司:
产品分类: 临床研究
公司分类: clinical_research
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
  • Description
  • ProductInfo
  • ShippingandStorage
  • Downloads
  • References

Description

Toremifeneisaselectiveestrogenreceptormodulator(SERM)thatalsomoderatesandrogenreceptoractivityaswell.Toremifenedisplaysanticancerchemotherapeuticandanti-angiogenicactivities.Clinically,thiscompoundisusedtotreatbreastcancerandprostatecancer.Toremifenedecreasesmicrovesseldensityandinducesremissionofbenignfibrouslesionsinclinicalsettingswithsubjectsexperiencingdesmoidtumors.Additionally,toremifeneincreaseslatencytotumorformation,decreasestumornumber,andincreasessurvivalinanimalmodelsofprostatecancer.

ProductInfo

CasNo.

89778-26-7

Purity

≥98%

Formula

C26H28ClNO

FormulaWt.

405.96

ChemicalName

2-[4-[(1Z)-4-Chloro-1,2-diphenyl-1-butenyl]phenoxy]-N,N-dimethylethanamine

IUPACName

2-[4-[(Z)-4-chloro-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethylethanamine

Synonym

Toremifene

MeltingPoint

108-110°C

Appearance

WhiteCrystalPowder

ShippingandStorage

StoreTemp

Ambient

ShipTemp

Ambient

Downloads

MSDS

T5769MSDSPDF

InfoSheet

T5769InfoSheetPDF

References

ChangBY,KimSA,MallaB,etal.TheEffectofSelectiveEstrogenReceptorModulators(SERMs)ontheTamoxifenResistantBreastCancerCells.ToxicolRes.2011Jun;27(2):85-93.PMID:24278556.

KawashimaH,TanakaT,ChengJS,etal.Effectofanti-estrogensontheandrogenreceptoractivityandcellproliferationinprostatecancercells.UrolRes.2004Dec;32(6):406-10.PMID:15316697.

HeidemannJ,OgawaH,OttersonMF,etal.Antiangiogenictreatmentofmesentericdesmoidtumorswithtoremifeneandinterferonalfa-2b:reportoftwocases.DisColonRectum.2004Jan;47(1):118-22.PMID:14719159.

RaghowS,HooshdaranMZ,KatiyarS,etal.Toremifenepreventsprostatecancerinthetransgenicadenocarcinomaofmouseprostatemodel.CancerRes.2002Mar1;62(5):1370-6.PMID:11888907.

品牌介绍
LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。 试剂