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当前位置: 首页 > 产品中心 > clinical_research > LKT/BROMPHENIRAMINE MALEATE/B7058/100 mg
商品详细LKT/BROMPHENIRAMINE MALEATE/B7058/100 mg
LKT/BROMPHENIRAMINE MALEATE/B7058/100 mg
LKT/BROMPHENIRAMINE MALEATE/B7058/100 mg
商品编号: B7058-100mg
品牌: lktlabs
市场价: ¥10480.00
美元价: 6288.00
产地: 美国(厂家直采)
公司:
产品分类: 临床研究
公司分类: clinical_research
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
  • Description
  • ProductInfo
  • ShippingandStorage
  • Downloads
  • References

Description

Brompheniramineisahalogenatedantihistaminederivativeofpheniraminethatexhibitsanticholinergicandneuromodulatoryactivities.BrompheniramineinhibitstheH1histaminereceptorandalsodisplaysnon-selectiveinhibitionofmuscarinicacetylcholinereceptors(mAChRs).Brompheniramineinhibitshistamine-inducedvasodilationandalsopotentiatestheeffectsofopioidanalgesics.Additionally,brompheniramineistheparentcompoundofzimelidine,aselectiveSEROtoninreuptakeinhibitor(SSRI)thatexhibitsantidepressantactivity;zimelidineinhibitspre-synaptic5-HTreuptakeandmayinhibittheserotonintransporter(SERT)ormonoamineoxidaseB(MAO-B).

ProductInfo

Purity

≥98%

Formula

C16H19BrN2•C4H4O4

FormulaWt.

435.31

IUPACName

3-(4-bromophenyl)-N,N-dimethyl-3-pyridin-2-ylpropan-1-amine;(Z)-but-2-enedioicacid

Appearance

Whitetooffwhitepowder

ShippingandStorage

StoreTemp

Ambient

ShipTemp

Ambient

Downloads

InfoSheet

B7058InfoSheetPDF

References

EgashiraT,TakayamaF,YamanakaY.Theinhibitionofmonoamineoxidaseactivitybyvariousantidepressants:differencesfoundinvariousmammalianspecies.JpnJPharmacol.1999Sep;81(1):115-21.PMID:10580379.

YasudaSU,YasudaRP.Affinitiesofbrompheniramine,chlorpheniramine,andterfenADIneatthefivehumanmuscariniccholinergicreceptorsubtypes.Pharmacotherapy.1999Apr;19(4):447-51.PMID:10212017.

TatsumiM,GroshanK,BlakelyRD,etal.Pharmacologicalprofileofantidepressantsandrelatedcompoundsathumanmonoaminetransporters.EurJPharmacol.1997Dec11;340(2-3):249-58.PMID:9537821.

DachmanWD,BedaridaG,BlaschkeTF,etal.Histamine-inducedvenodilationinhumanbeingsinvolvesbothH1andH2receptorsubtypes.JAllergyClinImmunol.1994Mar;93(3):606-14.PMID:8151062.

OgrenSO,RossSB,HallH,etal.Thepharmacologyofzimelidine:a5-HTselectivereuptakeinhibitor.ActaPsychiatrScandSuppl.1981;290:127-51.PMID:6452789.

品牌介绍
LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。 试剂