>
产品中心 >
clinical_research >
LKT/C-TYPE NATRIURETIC PEPTIDE (1-22), PIG/HUMAN/RAT/C5260/1 mg
C-typenatriureticpeptide(CNP)isanendogenouspeptideexpressedinthecentralnervoussystem,bone,andvasculature;CNP-22isamatureformofCNPthatisfoundpredominantlyinplasma.CNPexhibitsvasodilatory,natriuretic,diuretic,andcardioprotectiveactivities.CNPalsoexhibitsanti-fibroticpotential,regulatingcardiachypertrophyandremodeling.Thispeptideinhibitstherenin-angiotensinsystem,increasingendothelialpermeABIlity,andplaysaroleinbonegrowth.
| Purity | ≥95% |
|---|---|
| Formula | C93H157N27O28S3 |
| FormulaWt. | 2797.61 |
| Synonym | CNP |
| Appearance | Whitetooffwhitepowder |
| StoreTemp | -20°C |
|---|---|
| ShipTemp | Ambient |
| InfoSheet | C5260InfoSheetPDF |
|---|
DelRyS.C-typenatriureticpeptide:anewcardiacmediator.Peptides.2013Feb;40:93-8.PMID:23262354.
CalvieriC,RubattuS,VolpeM.Molecularmechanismsunderlyingcardiacantihypertrophicandantifibroticeffectsofnatriureticpeptides.JMolMed(Berl).2012Jan;90(1):5-13.PMID:21826523.
NishikimiT,KuwaharaK,NakaoK.Currentbiochemistry,molecularBIOLOGy,andclinicalrelevanceofnatriureticpeptides.JCardiol.2011Mar;57(2):131-40.Erratumin:JCardiol.2012Jan;59(1):98-9.PMID:21296556.
DelRyS,PassinoC,EmdinM,etal.C-typenatriureticpeptideandheartfailure.PharmacolRes.2006Nov;54(5):326-33.PMID:16904335.
