Description
Clopidogrel is a first generation thienopyridine P2Y12 receptor inhibitor. Clopidogrel acts as a cardioprotective antithrombotic/anticoagulant that is clinically used to treat coronary artery disease and peripheral vascular disease and also to prevent myocardial infarction and stroke.
References
Thomas MR, Storey RF. Impact of aspirin dosing on the effects of P2Y12 inhibition in patients with acute coronary syndromes. J Cardiovasc Transl Res. 2014 Feb;7(1):19-28. PMID: 24309957.
Ferri N, Corsini A, Bellosta S. Pharmacology of the new P2Y12 receptor inhibitors: insights on pharmacokinetic and pharmacodynamic properties. Drugs. 2013 Oct;73(15):1681-709. PMID: 24114622.
Sato Y, Miyashita A, Iwatsubo T, Usui T. Conclusive identification of the oxybutynin-hydrolyzing enzyme in human liver. Drug Metab Dispos. 2012 May;40(5):902-906. PMID: 22293119.