LKT/地奥司明/D3357/5克-免疫在线蚂蚁淘旗下平台

商品详细LKT/地奥司明/D3357/5克

LKT/地奥司明/D3357/5克

商品编号： D3357-5g

品牌： lktlabs

市场价： ¥880.00

美元价： 528.00

产地：美国(厂家直采)

公司：

产品分类：临床研究

公司分类： clinical_research

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

ProductIDD3357

CasNo.520-27-4

Purity≥95%

Description
ProductInfo
ShippingandStorage
Downloads
References

Description

DiosminisaflavonefoundinTeucriumthatexhibitsneuroprotective,cardioprotective,antioxidative,anti-hyperlipidemic,anticancer,chemopreventive,andanti-inflammatoryactivities.Diosminalleviatesneurologicaldeficits,decreasesinfarctvolume,andupregulatesexpressionofpJAK2,pSTAT3,andBcl-2inanimalmodelsofcerebralischemia/reperfusioninjury.DiosminalsoactsasarADIcalscavengerandincreasesantioxidativeenzymeactivity,improvingcardiacfunctioninotheranimalmodels.Inanimalmodelsofretinalischemia/reperfusion,diosmindecreasesretinaledemaandextravasation.Additionally,diosmindecreaseslipidperoxidationandincreasesHMGCoAreductaseinanimalmodelsofmyocardialinfarction.Thiscompoundalsoinhibitsproliferationofhepatocellularcarcinomacellsandprevents2-AAF-inducedcarcinogenesisinvivo.

ProductInfo

CasNo.	520-27-4
Purity	≥95%
Formula	C₂₈H₃₂O₁₅
FormulaWt.	608.54
ChemicalName	7-[[6-O-(6-Deoxy-a-L-mannopyranosyl)-β-D-gluco-pyranosyl]oxy]-5-hydroxy-2-(3-hydroxy-4-methoxy-phenyl)-4H-1-benzopyran-4-one
IUPACName	5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxychromen-4-one
Synonym	Diosmil;Diovenor;Flebosmil;Hemerven;Insuven;Litosmil;Tovene;Varinon;Venosmine
MeltingPoint	274°C(dec)
Appearance	LightYellowPowder

ShippingandStorage

StoreTemp	Ambient
ShipTemp	Ambient

Downloads

MSDS	D3357MSDSPDF
InfoSheet	D3357InfoSheetPDF

References

SenthamizhselvanO,ManivannanJ,SilambarasanT,etal.Diosminpretreatmentimprovescardiacfunctionandsuppressesoxidativestressinratheartafterischemia/reperfusion.EurJPharmacol.2014Aug5;736:131-7.PMID:24769512.

LiuX,ZhangX,ZhangJ,etal.Diosminprotectsagainstcerebralischemia/reperfusioninjurythroughactivatingJAK2/STAT3signalpathwayinmice.Neuroscience.2014May30;268:318-27.PMID:24680937.

QueenthySS,JohnB.Diosminexhibitsanti-hyperlipidemiceffectsinisoproterenolinducedmyocardialinfarctedrats.EurJPharmacol.2013Oct15;718(1-3):213-8.PMID:24036254.

TahirM,RehmanMU,LateefA,etal.Diosminabrogateschemicallyinducedhepatocarcinogenesisviaalleviationofoxidativestress,hyperproliferativeandinflammatoryMarkersinmurinemodel.ToxicolLett.2013Jul18;220(3):205-18.PMID:23665045.

TongN,ZhangZ,ZhangW,etal.Diosminalleviatesretinaledemabyprotectingtheblood-retinalbarrierandreducingretinalvascularpermeABIlityduringischemia/reperfusioninjury.PLoSOne.2013Apr24;8(4):e61794.PMID:23637907.

品牌介绍

LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供：癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的，为全球提供先端的药物研发试剂、试剂盒、委托合成，并为药物生产企业提供原料，最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。试剂