LKT/ECHINACOSIDE/E0929/5 mg-免疫在线蚂蚁淘旗下平台

商品详细LKT/ECHINACOSIDE/E0929/5 mg

LKT/ECHINACOSIDE/E0929/5 mg

商品编号： E0929-5mg

品牌： lktlabs

市场价： ¥1480.00

美元价： 888.00

产地：美国(厂家直采)

公司：

产品分类：临床研究

公司分类： clinical_research

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

ProductIDE0929

CasNo.82854-37-3

Purity≥98%

Description
ProductInfo
ShippingandStorage
Downloads
References

Description

EchinacosideisaphenylethanoidglycosidefoundinEchinacea,amongothersources;itexhibitsneuroprotectiveandvasodilatoryactivities.Invivo,echinacosideinhibitscytochromecreleaseandcaspase-3activationthroughmodulationofERKsignaling,resultinginneuroprotectioninamodelofmiddlecerebralarteryocclusion.EchinacosidealsodisplaysneuroprotectivebenefitinaMTPT-inducedmousemodelofParkinson’sDisease,decreasingtheBax/Bcl-2ratioandinhibitingsuppressionofdopamineanddopaminetransporter(DAT)levels.ThiscompoundincreasescGMPinrataorticrings,inducingvasodilation.Additionally,echinacosideimprovesbonemineraldensityandmicroarchitecture,decreasingRANKLexpressionandincreasingesteoprotegerinlevelsinanimalmodelsofosteopenia.

ProductInfo

CasNo.	82854-37-3
Purity	≥98%
Formula	C₃₅H₄₆O₂₀
FormulaWt.	786.73
IUPACName	[(2R,3R,4R,5R,6R)-6-[2-(3,4-dihydroxyphenyl)ethoxy]-5-hydroxy-2-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl](E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
Solubility	Solubleinwaterandethanol.
Appearance	Whitetooffwhitepowder

ShippingandStorage

StoreTemp	Ambient
ShipTemp	Ambient

Downloads

InfoSheet	E0929InfoSheetPDF

References

YangX,LiF,YangY,etal.Efficacyandsafetyofechinacosideinaratosteopeniamodel.EvidBasedComplementAlternatMed.2013;2013:926928.PMID:23573159.

ZhuM,LuC,LiW.TransientexposuretoechinacosideissufficienttoactivateTrksignalingandprotectneuronalcellsfromrotenone.JNeuRochem.2013Feb;124(4):571-80.PMID:23189969.

WeiLL,ChenH,JiangY,etal.Effectsofechinacosideonhistio-centrallevelsofactivemassinmiddlecerebralarteryocclusionrats.BiomedEnvironSci.2012Apr;25(2):238-44.PMID:22998833.

ZhaoQ,GaoJ,LiW,etal.NeurotrophicandneurorescueeffectsofEchinacosideinthesubacuteMPTPmousemodelofParkinson"sdisease.BrainRes.2010Jul30;1346:224-36.PMID:20478277.

HeWJ,FangTH,MaX,etal.Echinacosideelicitsendothelium-dependentrelaxationinrataorticringsviaanNO-cGMPpathway.PlantaMed.2009Oct;75(13):1400-4.PMID:19468974.

品牌介绍

LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供：癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的，为全球提供先端的药物研发试剂、试剂盒、委托合成，并为药物生产企业提供原料，最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。试剂