LKT/RESVERATROL/R1776/100 mg-免疫在线蚂蚁淘旗下平台

商品详细LKT/RESVERATROL/R1776/100 mg

LKT/RESVERATROL/R1776/100 mg

商品编号： R1776-100mg

品牌： lktlabs

市场价： ¥760.00

美元价： 456.00

产地：美国(厂家直采)

公司：

产品分类：临床研究

公司分类： clinical_research

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Product ID R1776

Cas No. 501-36-0

Purity ≥98%

Description
Product Info
Shipping and Storage
Downloads
References

Description

Resveratrol and its metabolites are phenolic phytoalexins found in several plants such as soybeans, peanuts, blueberries, mulberries, and grapes. Resveratrol is most well known for its antioxidative effects and activation of SIRT1, both contributing to its cardioprotective, anticancer chemotherapeutic, chemopreventive, anti-aging, anti-inflammatory, and antiviral activities; it also acts as a phytoestrogen. Resveratrol reversibly inhibits MAO as well as synaptosomal 5-HT and NE uptake, indicating potential antidepressant activity. This compound also shows benefit in in vitro and in vivo models of Alzheimer’s disease, degrading amyloid-β (Aβ) plaques, increasing brain cysteine levels, and decreasing brain glutathione levels; these effects may be dependent on resveratrol’s activation of AMPK and/or proteasomes.

Product Info

Cas No.	501-36-0
Purity	≥98%
Formula	C₁₄H₁₂O₃
Formula Wt.	228.24
Chemical Name	1,3-Benzenediol, 5-(2-(4-hydroxyphenyl)ethenyl)-, (E)-
IUPAC Name	5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol
Synonym	3,4',5-Stilbenetrio; 3,4',5-Trihydroxystilbene
Melting Point	254°C
Solubility	Soluble in DMSO and ethanol.
Appearance	White Powder

Shipping and Storage

Store Temp	-20°C
Ship Temp	Ambient

Downloads

MSDS	R1776 MSDS PDF
Info Sheet	R1776 Info Sheet PDF
Brochures	Resveratrol Flyer

References

Mohar DS, Malik S. The Sirtuin System: The Holy Grail of Resveratrol? J Clin Exp Cardiolog. 2012 Nov;3(11). 216. PMID: 23560248.

Vingtdeux V, Giliberto L, Zhao H, et al. AMP-activated protein kinase signaling activation by resveratrol modulates amyloid-beta peptide metabolism. J Biol Chem. 2010 Mar 19;285(12):9100-13. PMID: 20080969.

Karuppagounder SS, Pinto JT, Xu H, et al. Dietary supplementation with resveratrol reduces plaque pathology in a transgenic model of Alzheimer's disease. Neurochem Int. 2009 Feb;54(2):111-8. PMID: 19041676.

Athar M, Back JH, Tang X, et al. Resveratrol: a review of preclinical studies for human cancer prevention. Toxicol Appl Pharmacol. 2007 Nov 1;224(3):274-83. PMID: 17306316.

Yáñez M, Fraiz N, Cano E, et al. Inhibitory effects of cis- and trans-resveratrol on noradrenaline and 5-hydroxytryptamine uptake and on monoamine oxidase activity. Biochem Biophys Res Commun. 2006 Jun 2;344(2):688-95. PMID: 16631124.

Marambaud P, Zhao H, Davies P. Resveratrol promotes clearance of Alzheimer's disease amyloid-beta peptides. J Biol Chem. 2005 Nov 11;280(45):37377-82. PMID: 16162502.

Narayanan N, Nargi D, Randolph C, et al. Liposome encapsulation of curcumin and resveratrol in combination reduces prostate cancer incidence in PTEN knockout mice. Int J Cancer. 2009 Feb 6;125(1):1-8. PMID: 19326431.

Huang A, Yang YM, Yan C, et al. Altered MAPK signaling in progressive deterioration of endothelial function in diabetic mice. Diabetes. 2012 Dec;61(12):3181-3188. PMID: 22933112.

Back JH, Rezvani HR, Zhu Y, et al. Cancer cell survival following DNA damage-mediated premature senescence is regulated by mammalian target of rapamycin (mTOR)-dependent inhibition of sirtuin 1. J Biol Chem. 2011 May 27;286(21):19100-19108. PMID: 21471201.

品牌介绍

LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供：癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的，为全球提供先端的药物研发试剂、试剂盒、委托合成，并为药物生产企业提供原料，最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。试剂