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当前位置: 首页 > 产品中心 > clinical_research > LKT/RESVERATROL/R1776/500 mg
商品详细LKT/RESVERATROL/R1776/500 mg
LKT/RESVERATROL/R1776/500 mg
LKT/RESVERATROL/R1776/500 mg
商品编号: R1776-500mg
品牌: lktlabs
市场价: ¥2520.00
美元价: 1512.00
产地: 美国(厂家直采)
公司:
产品分类: 临床研究
公司分类: clinical_research
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
  • Description
  • ProductInfo
  • ShippingandStorage
  • Downloads
  • References

Description

Resveratrolanditsmetabolitesarephenolicphytoalexinsfoundinseveralplantssuchassoybeans,peanuts,blueberries,mulberries,andgrapes.ResveratrolismostwellknownforitsantioxidativeeffectsandactivationofSIRT1,bothcontributingtoitscardioprotective,anticancerchemotherapeutic,chemopreventive,anti-aging,anti-inflammatory,andantiviralactivities;italsoactsasaphytoestrogen.ResveratrolreversIBLyinhibitsMAOaswellassynaptosomal5-HTandNEuptake,indicatingpotentialantidepressantactivity.ThiscompoundalsoshowsbenefitininvitroandinvivomodelsofAlzheimer’sdisease,degrADIngamyloid-β(Aβ)plaques,increasingbraincysteinelevels,anddecreasingbrainglutathionelevels;theseeffectsmaybedependentonresveratrol’sactivationofAMPKand/orproteasomes.

ProductInfo

CasNo.

501-36-0

Purity

≥98%

Formula

C14H12O3

FormulaWt.

228.24

ChemicalName

1,3-Benzenediol,5-(2-(4-hydroxyphenyl)ethenyl)-,(E)-

IUPACName

5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol

Synonym

3,4",5-Stilbenetrio;3,4",5-Trihydroxystilbene

MeltingPoint

254°C

Solubility

SolubleinDMSOandethanol.

Appearance

WhitePowder

ShippingandStorage

StoreTemp

-20°C

ShipTemp

Ambient

Downloads

MSDS

R1776MSDSPDF

InfoSheet

R1776InfoSheetPDF

Brochures

ResveratrolFlyer

References

MoharDS,MalikS.TheSirtuinSystem:TheHolyGrailofResveratrol?JClinExpCardiolog.2012Nov;3(11).216.PMID:23560248.

VingtdeuxV,GilibertoL,ZhaoH,etal.AMP-activatedproteinkinasesignalingactivationbyresveratrolmodulatesamyloid-betapeptidemetabolism.JBiolChem.2010Mar19;285(12):9100-13.PMID:20080969.

KaruppagounderSS,PintoJT,XuH,etal.DietarysupplementationwithresveratrolreducesplaquepathologyinatransgenicmodelofAlzheimer"sdisease.NeuRochemInt.2009Feb;54(2):111-8.PMID:19041676.

AtharM,BackJH,TangX,etal.Resveratrol:areviewofpreclinicalstudiesforhumancancerprevention.ToxicolApplPharmacol.2007Nov1;224(3):274-83.PMID:17306316.

YáñezM,FraizN,CanoE,etal.Inhibitoryeffectsofcis-andtrans-resveratrolonnoradrenalineand5-hydroxytryptamineuptakeandonmonoamineoxidaseactivity.BiochemBiophysResCommun.2006Jun2;344(2):688-95.PMID:16631124.

MarambaudP,ZhaoH,DaviesP.ResveratrolpromotesclearanceofAlzheimer"sdiseaseamyloid-betapeptides.JBiolChem.2005Nov11;280(45):37377-82.PMID:16162502.

NarayananN,NargiD,RandolphC,etal.LiposomeencapsulationofcurcuminandresveratrolincombinationreducesprostatecancerincidenceinPTENknockoutmice.IntJCancer.2009Feb6;125(1):1-8.PMID:19326431.

HuangA,YangYM,YanC,etal.AlteredMAPKsignalinginprogressivedeteriorationofendothelialfunctionindiabeticmice.Diabetes.2012Dec;61(12):3181-3188.PMID:22933112.

BackJH,RezvaniHR,ZhuY,etal.CancercellsurvivalfollowingDNAdamage-mediatedprematuresenescenceisregulatedbymammaliantargetofrapamycin(mTOR)-dependentinhibitionofsirtuin1.JBiolChem.2011May27;286(21):19100-19108.PMID:21471201.

品牌介绍
LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。 试剂