LKT/S-（U2212）-五味子素B/S0831/5 mg-免疫在线蚂蚁淘旗下平台

商品详细LKT/S-（U2212）-五味子素B/S0831/5 mg

LKT/S-（U2212）-五味子素B/S0831/5 mg

商品编号： S0831-5mg

品牌： lktlabs

市场价： ¥2940.00

美元价： 1764.00

产地：美国(厂家直采)

公司：

产品分类：临床研究

公司分类： clinical_research

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

ProductIDS0831

CasNo.61281-37-6

Purity≥98%

Description
ProductInfo
ShippingandStorage
Downloads
References

Description

SchisandrinBisfoundinSchisandra;itexhibitsanti-fibrotic,anti-inflammatory,cardioprotective,hepatoprotective,neuroprotective,andanti-metastaticactivities.Invitro,schisandrinBdecreasesTGF-β1-inducedmyosinlightchainphosphorylationandSmadsignaling,preventingstressfiberformation.Inanimalmodelsofmyocardialinfarction,schisandrinBdownregulatesexpressionofpro-inflammatorycytokinesandinhibitsmyocardialapoptosis,decreasinginfarctsizeandimprovingheartfunctionandsurvivalrates.SchisandrinBalsoincreasesexpressionofHSP27andHSP70,inhibitingacetaminophen-inducedliverinjuryandhepaticnecrosis.Inanimalmodelsofcerebralischemia/reperfusion,thiscompounddecreasesexpressionofIL-1βandTNF-αandpreventsdegradationofmatrixmetalloproteinases2and9(MMP2/9),decreasinginfarctvolume.Additionally,schisandrinBinhibitsinvasionofbreastcancercellsbysuppressingtheepithelialtomesenchymaltransition(EMT),increasingsurvivalratesinvivo.

ProductInfo

CasNo.	61281-37-6
Purity	≥98%
Formula	C₂₃H₂₈O₆
FormulaWt.	400.47
ChemicalName	Benzo(3,4)cycloocta(1,2-f)(1,3)benzodioxole,5,6,7,8-tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethyl-,stereoisomer
Synonym	γ-Schisandrin;S(-)WuweizisuB;S(-)SchizandrinB
MeltingPoint	100-102°C
Appearance	WhiteCrystalPowder

ShippingandStorage

StoreTemp	4°C
ShipTemp	Ambient

Downloads

InfoSheet	S0831InfoSheetPDF

References

ChunJN,KimSY,ParkEJ,etal.SchisandrinBsuppressesTGFβ1-inducedstressfiberformationbyinhibitingmyosinlightchainphosphorylation.JEthnopharmacol.2014Mar14;152(2):364-71.PMID:24486209.

LiL,ZhangT,ZhouL,etal.SchisandrinBattenuatesacetaminophen-inducedhepaticinjurythroughheat-shockprotein27and70inmice.JGastroenterolHepatol.2014Mar;29(3):640-7.PMID:24219791.

ChenP,PangS,YangN,etal.BeneficialeffectsofschisandrinBonthecardiacfunctioninmicemodelofmyocardialinfarction.PLoSOne.2013Nov8;8(11):e79418.PMID:24260217.

LeeTH,JungCH,LeeDH.NeuroprotectiveeffectsofSchisandrinBagainsttransientfocalcerebralischemiainSprague-Dawleyrats.FoodChemToxicol.2012Dec;50(12):4239-45.PMID:22960133.

LiuZ,ZhangB,LiuK,etal.SchisandrinBattenuatescancerinvasionandmetastasisviainhibitingepithelial-mesenchymaltransition.PLoSOne.2012;7(7):e40480.PMID:22848381.

品牌介绍

LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供：癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的，为全球提供先端的药物研发试剂、试剂盒、委托合成，并为药物生产企业提供原料，最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。试剂