LKT/NIMODIPINE/N3448/5 g-免疫在线蚂蚁淘旗下平台

商品详细LKT/NIMODIPINE/N3448/5 g

LKT/NIMODIPINE/N3448/5 g

商品编号： N3448-5g

品牌： lktlabs

市场价： ¥12720.00

美元价： 7632.00

产地：美国(厂家直采)

公司：

产品分类：临床研究

公司分类： clinical_research

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

ProductIDN3448

CasNo.66085-59-4

Purity≥98%

Description
ProductInfo
ShippingandStorage
Downloads
References

Description

NimodipineisanantagoNISTatL-typeCa2+channelsthatexhibitsantihypertensive,neuroprotective,neuromodulatory,cognitionenhancing,andanti-inflammatoryactivities.Inanimalmodelsofsubarachnoidhemorrhage,nimodipinepreventscerebralischemiaandvasospasm.Nimodipinealsoinhibitsmethylmercury-inducedbehavioralneurotoxicityinvivo.InanimalmodelsofAlzheimer’sdisease,nimodipineinhibitsamyloid-β(Aβ)-stimulatedreleaseofIL-1βandresultingneurotoxicity.Thiscompoundalsoinhibitsneurologicalsymptomsofdrug-inducedwithdrawal,suppressinganxiety,depression,andmemoryimpairment.

ProductInfo

CasNo.	66085-59-4
Purity	≥98%
Formula	C₂₁H₂₆N₂O₇
FormulaWt.	418.44
ChemicalName	1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylicacid2-methoxyethyl1-methyl-ethylester
IUPACName	3-O-(2-methoxyethyl)5-O-propan-2-yl2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Synonym	Periplum;Nimotop
MeltingPoint	125°C
Solubility	SolubleinmethanolorDMSO.Insolubleinwater.
Appearance	Lightyellowcrystallinepowder

ShippingandStorage

StoreTemp	ambient
ShipTemp	Ambient

Downloads

MSDS	N3448MSDSPDF
InfoSheet	N3448InfoSheetPDF

References

BiaAGY,PolakP,MichalakA,etal.Influenceofcalciumchannelantagonistsonnonsomaticsignsofnicotineandd-amphetaminewithdrawalinmice.PharmacolRep.2014Apr;66(2):212-22.PMID:24911072.

BaileyJM,HutsellBA,NewlandMC.Dietarynimodipinedelaystheonsetofmethylmercuryneurotoxicityinmice.Neurotoxicology.2013Jul;37:108-17.PMID:23583802.

SanzJM,ChiozziP,ColaiannaM,etal.NimodipineinhibitsIL-1βreleasestimulatedbyamyloidβfrommicroglia.BrJPharmacol.2012Dec;167(8):1702-11.PMID:22831460.

SharmaN,ChoDH,KimSY,etal.MagnesiumsulfatesuppressesL-typecalciumcurrentsonthebasilararterysmoothmusclecellsinrabbits.NeurolRes.2012Apr;34(3):291-6.PMID:22450340.

JanjuaN,MayerSA.Cerebralvasospasmaftersubarachnoidhemorrhage.CurrOpinCritCare.2003Apr;9(2):113-9.PMID:12657973.

品牌介绍

LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供：癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的，为全球提供先端的药物研发试剂、试剂盒、委托合成，并为药物生产企业提供原料，最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。试剂