4000-520-616
欢迎来到免疫在线!(蚂蚁淘生物旗下平台)  请登录 |  免费注册 |  询价篮
主营:主营:防癌抗癌特殊化学品试剂
咨询热线电话
4000-520-616
当前位置: 首页 > 产品中心 > clinical_research > LKT/NOTOGINSENOSIDE R1/N5778/10 mg
商品详细LKT/NOTOGINSENOSIDE R1/N5778/10 mg
LKT/NOTOGINSENOSIDE R1/N5778/10 mg
LKT/NOTOGINSENOSIDE R1/N5778/10 mg
商品编号: N5778-10mg
品牌: lktlabs
市场价: ¥5980.00
美元价: 3588.00
产地: 美国(厂家直采)
公司:
产品分类: 临床研究
公司分类: clinical_research
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
  • Description
  • ProductInfo
  • ShippingandStorage
  • Downloads
  • References

Description

NotoginsenosideR1isatriterpenesaponinoriginallyfoundinspeciesofPanax(ginseng)thatexhibitsneuroprotective,anti-atherosclerotic,anti-inflammatory,anti-hyperlipidemic,andimmunostimulatoryactivities.NotoginsenosideR1decreasesamyloid-β-inducedoxidativedamageandMAPKsignaling,improvingcellviABIlityincellularmodelsofAlzheimer’sdisease.InApoEknockoutanimals,notoginsenosideR1increasesexpressionofglutathioneandsuperoxidedismutaseanddecreasesexpressionofinflammatorycytokines;italsodecreasesLDL,triglyceride,andcholesterollevelsandincreasesHDLlevels,preventingatheroscleroticlesions.Thiscompoundalsoincreasesantigen-inducedspleenocyteproliferationandIgGtitersinvivo.

ProductInfo

CasNo.

80418-24-2

Purity

≥98%

Formula

C47H80O18

FormulaWt.

933.13

IUPACName

(2S,3R,4S,5S,6R)-2-[(2S)-2-[(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-6-[(2R,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxyoxan-2-yl]oxy-3,12-dihydroxy-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-methylhept-5-en-2-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol

Solubility

SolubleinDMSO.

Appearance

WhitePowder

ShippingandStorage

StoreTemp

4°C

ShipTemp

Ambient

Downloads

InfoSheet

N5778InfoSheetPDF

References

MaB,MengX,WangJ,etal.NotoginsenosideR1attenuatesamyloid-β-induceddamageinneuronsbyinhibitingreactiveoxygenspeciesandmodulatingMAPKactivation.IntImmunopharmacol.2014Jun24;22(1):151-159.PMID:24975829.

JiaC,XiongM,WangP,etal.NotoginsenosideR1AttenuatesAtheroscleroticLesionsinApoEDeficientMouseModel.PLoSOne.2014Jun16;9(6):e99849.PMID:24933211.

SunHX,ChenY,YeY.GinsenosideReandnotoginsenosideR1:Immunologicadjuvantswithlowhaemolyticeffect.ChemBiodivers.2006Jul;3(7):718-26.PMID:17193304.

品牌介绍
LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。 试剂