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商品详细LKT/原儿茶醛/P7058/100克
LKT/原儿茶醛/P7058/100克
LKT/原儿茶醛/P7058/100克
商品编号: P7058-100g
品牌: lktlabs
市场价: ¥6740.00
美元价: 4044.00
产地: 美国(厂家直采)
公司:
产品分类: 临床研究
公司分类: clinical_research
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
  • Description
  • ProductInfo
  • ShippingandStorage
  • Downloads
  • References

Description

Protocatechuicaldehydeisapolyphenolfoundinmanyplantsandfoods;itexhibitsanti-inflammatory,cardioprotective,anti-atherosclerotic,andhepatoprotectiveactivities.Inanimalmodelsofischemia/reperfusion,protocatechuicaldehydedecreaseslevelsofcreatinekinase-MB,troponin-1,TNF-α,IL-6,intracellularadhesionmolecule1(ICAM-1),andinhibitorofκBkinase(IKK)andpreventsactivationofNF-κB,decreasinginfarctsize.Additionally,protocatechuicaldehydedecreasesactivityofhigh-mobilitygroupbox1(HMGB1)protein,decreasinglevelsofmyeloperoxidaseandactivationofNF-κBandpreventingsepsisinanimalmodels.Thiscompoundalsodecreasesactivationofcaspase3inendothelialcells,preventingapoptosis.Inanimalmodelsofliverfibrosis,protocatechuicaldehydedecreaseslevelsofcollagen,TGF-β,andconnectivetransforminggrowthfactor(CTGF).

ProductInfo

CasNo.

139-85-5

Purity

≥98%

Formula

C7H6O3

FormulaWt.

138.12

ChemicalName

3,4-Dihydroxybenzaldehyde

IUPACName

3,4-dihydroxybenzaldehyde

MeltingPoint

153°C

Solubility

6310mg/LH2O

Appearance

Whitetooffwhitepowder

ShippingandStorage

StoreTemp

Ambient

ShipTemp

Ambient

Downloads

InfoSheet

P7058InfoSheetPDF

References

WeiG,GuanY,YinY,etal.Anti-inflammatoryeffectofprotocatechuicaldehydeonmyocardialischemia/reperfusioninjuryinvivoandinvitro.Inflammation.2013Jun;36(3):592-602.PMID:23269534.

XingYL,ZhouZ,Agula,etal.Protocatechuicaldehydeinhibitslipopolysaccharide-inducedhumanumbilicalveinendothelialcellapoptosisviaregulationofcaspase-3.PhytotherRes.2012Sep;26(9):1334-41.PMID:22298410.

XuY,JiangWL,ZhangSP,etal.Protocatechuicaldehydeprotectsagainstexperimentalsepsisinvitroandinvivo.BasicClinPharmacolToxicol.2012Apr;110(4):384-9.PMID:22050905.

品牌介绍
LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。 试剂