Description
ProtopanaxatriolisatriterpenesapogeninoriginallyfoundinspeciesofPanax(ginseng)thatexhibitsantihypertensive,neuromodulatory,andantioxidativeactivities.ProtopanaxatriolpreventsbreakdownofvitaminD3andinhibitsGABA-AandGABA-Creceptorsaswellasslow-activatingdelayedrectifierK+channels.ProtopanaxatriolalsostimulatesproductionofeNOSandNO,increasingvascularrelaxationanddecreasingbloodpressure.Inanimalmodelsofisoproterenol-inducedmyocardialinjury,protopanaxatrioldecreaseslevelsofmaldionaldehydeandincreasesactivityofsuperoxidedismutaseandglutathioneperoxidase.
References
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