LKT/葛根素/P8118/500毫克-免疫在线蚂蚁淘旗下平台

商品详细LKT/葛根素/P8118/500毫克

LKT/葛根素/P8118/500毫克

商品编号： P8118-500mg

品牌： lktlabs

市场价： ¥4040.00

美元价： 2424.00

产地：美国(厂家直采)

公司：

产品分类：临床研究

公司分类： clinical_research

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

ProductIDP8118

CasNo.3681-99-0

Purity≥96%

Description
ProductInfo
ShippingandStorage
Downloads
References

Description

PuerarinisanisoflavonederivativeofdaidzeinfoundinPueraria(RADIx);itexhibitsanxiolytic,cardioprotective,neuroprotective,andantioxidativeactivities.Thiscompoundalsoactsasaphytoestrogen.PuerarinactsasanantagoNISTat5-HT2CreceptorsandatthebenzodiazepinesiteonGABA-Areceptors.PuerarinincreasessocialinteractiontimeandlocomotoractivityinanimalmodelsofsubstancewithdrawalandinhibitscognitiveimpairmentintheMorriswatermazeparadigminanimalmodelsofAlzheimer’sdisease.Additionally,puerarindecreasessystolicbloodpressureandheartrateanddownregulatesexpressionofP2X3receptorsinanimalmodelsofmyocardialischemia/reperfusion.ThiscompoundalsoprotectsneuronsagainstH2O2-inducedoxidativestressinvitro.

ProductInfo

CasNo.	3681-99-0
Purity	≥96%
Formula	C₂₁H₂₀O₉
FormulaWt.	416.38
ChemicalName	8-β-D-glucopyranosyl-7-hydroxy-3-(4-hydroxyphenyl)-(9CI)4H-1-Benzopyran-4-one
IUPACName	7-hydroxy-3-(4-hydroxyphenyl)-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]chromen-4-one
MeltingPoint	187°C
Solubility	Solubleinmethanol.Slightlysolubleinethanol.
Appearance	Whitepowderwithyellowcast

ShippingandStorage

StoreTemp	Ambient
ShipTemp	Ambient

Downloads

InfoSheet	P8118InfoSheetPDF

References

LiuS,YuS,XuC,etal.PuerarinalleviatesaggravatedsympathoexcitatoryresponseinducedbymyocardialischemiaviaregulatingP2X3receptorinratsuperiorcervicalganglia.NeuRochemInt.2014May;70:39-49.PMID:24657446.

ZhouY,XieN,LiL,etal.PuerarinalleviatescognitiveimpairmentandoxidativestressinAPP/PS1transgenicmice.IntJNeuropsychopharmacol.2014Apr;17(4):635-44.PMID:24345484.

ZhangQ,HuangWD,LvXY,etal.PuerarinprotectsdifferentiatedPC12cellsfromH2O2-inducedapoptosisthroughthePI3K/Aktsignallingpathway.CellBiolInt.2012May1;36(5):419-26.PMID:22126839.

OverstreetDH,KralicJE,MorrowAL,etal.NPI-031G(puerarin)reducesanxiogeniceffectsofalcoholwithdrawalorbenzodiazepineinverseor5-HT2Cagonists.PharmacolBiochemBehav.2003Jun;75(3):619-25.PMID:12895679.

品牌介绍

LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供：癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的，为全球提供先端的药物研发试剂、试剂盒、委托合成，并为药物生产企业提供原料，最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。试剂