Schisandrin A is originally found in Schisandra; it exhibits cardioprotective, antioxidative, and antihypertensive activities. In animal models of cardiac ischemia/reperfusion, schisandrin A decreases infarct size, maldionaldehyde levels, left ventricular systolic and end diastolic pressures, and arrhythmia and prevents cardiomyocytes apoptosis. This compound also induces relaxation in rat thoracic aortas.
| Cas No. | 61281-38-7 |
|---|---|
| Purity | ≥98% |
| Formula | C24H32O6 |
| Formula Wt. | 416.51 |
| Chemical Name | Dibenzo(a,c)cyclooctene, 5,6,7,8-tetrahydro-1,2,3,10,11,12-hexamethoxy-6,7-dimethyl-, stereoisomer |
| Synonym | R(+) Schizandrin A; R(+) deoxyschisandrin A; R(+) deoxyschizandrin |
| Melting Point | 117-118°C |
| Appearance | White Crystal Powder |
| Store Temp | 4°C |
|---|---|
| Ship Temp | Ambient |
| Info Sheet | S0830 Info Sheet PDF |
|---|
Chang R, Li Y, Yang X, et al. Protective role of deoxyschizandrin and schisantherin A against myocardial ischemia-reperfusion injury in rats. PLoS One. 2013 Apr 19;8(4):e61590. PMID: 23620773.
Yang X, Wang Y, Zhang X, et al. Screening vasoconstriction inhibitors from traditional Chinese medicines using a vascular smooth muscle/cell membrane chromatography-offline-liquid chromatography-mass spectrometry. J Sep Sci. 2011 Oct;34(19):2586-93. PMID: 21898806.
