Description
Angiotensin peptides exhibit pressor (vasoconstrictive) activity through binding of the angiotensin II type 1 (AT1) receptor, increasing blood pressure and volume. Angiotensin I (AT I) is a cleavage product of angiotensin and serves no primary biological purpose other than to function as a precursor to angiotensin II.
References
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Herichova I, Szantoova K. Renin-angiotensin system: upgrade of recent knowledge and perspectives. Endocr Regul. 2013 Jan;47(1):39-52. PMID: 23363256.
Dupont AG, Brouwers S. Brain angiotensin peptides regulate sympathetic tone and blood pressure. J Hypertens. 2010 Aug;28(8):1599-610. PMID: 20502352.