Description
Angiotensinogenisalsoknownas“reninsubstrate,”andisaprecursorforallangiotensinpeptides.Angiotensinogenisanα-2-globulinproducedintheliverinresponsetoestrogen,thyroid,orcorticosteroidsignaling.Angiotensinogeniscleavedbyrenin,producingangiotensinI(ATI).
References
HerichovaI,SzantoovaK.Renin-angiotensinsystem:upgradeofrecentknowledgeandperspectives.EndocrRegul.2013Jan;47(1):39-52.PMID:23363256.
KoboriH,UrushiharaM.Augmentedintrarenalandurinaryangiotensinogeninhypertensionandchronickidneydisease.PflugersArch.2013Jan;465(1):3-12.PMID:22918624.