LKT/ANISODAMINE/A5334/100 mg-免疫在线蚂蚁淘旗下平台

商品详细LKT/ANISODAMINE/A5334/100 mg

LKT/ANISODAMINE/A5334/100 mg

商品编号： A5334-100mg

品牌： lktlabs

市场价： ¥840.00

美元价： 504.00

产地：美国(厂家直采)

公司：

产品分类：临床研究

公司分类： clinical_research

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

立即询价

商品介绍

ProductIDA5334

CasNo.55869-99-3

Purity≥98%

Description
ProductInfo
ShippingandStorage
Downloads
References

Description

AnisodamineisatropanealkaloidoriginallyfoundinplantsintheSolanaceaefamily;itexhibitsanti-inflammatoryactivityandisclinicallyusedtoinduceatropinizationinorganophosphatepoisoningsubjectsandtoimproveacutelunginjurypathologyandrespiratoryparameters.Anisodamineinhibitsα1-adrenergicreceptorsandmuscarinicacetylcholinereceptors(mAChRs).Anisodamineisalsoclinicallyusedtotreatacuteglomerulonephritisanddiabeticnephropathy,andalsotoimproverenalmicrocirculation.Additionally,anisodaminedecreasesexpressionofVEGFandICAM-1andsuppressesinflammatorycellinfiltrationandproliferation,decreasingperivascularhemorrhageinanimalmodelsofphlebitis.

ProductInfo

CasNo.	55869-99-3
Purity	≥98%
Formula	C₁₇H₂₃NO₄
FormulaWt.	305.37
ChemicalName	α-(hydroxymethyl)benzeneaceticacid-6-hydroxy-8-methyl-8-azABIcyclo(3.2.1)oct-3-ylester
IUPACName	[(3S,6S)-6-hydroxy-8-methyl-8-azabicyclo[3.2.1]octan-3-yl](2S)-3-hydroxy-2-phenylpropanoate
Synonym	6-Hydroxyhyoscyamine
MeltingPoint	103-113°C
Appearance	Whitecrystallinepowder

ShippingandStorage

StoreTemp	Ambient
ShipTemp	Ambient

Downloads

MSDS	A5334MSDSPDF
InfoSheet	A5334InfoSheetPDF

References

WangW,ChenQF,LiQB,etal.Efficiencyofanisodaminefororganophosphorus-poisonedpatientswhenatropinizationcannotbeachievedwithhighdosesofatropine.EnvironToxicolPharmacol.2014Mar;37(2):477-81.PMID:24561530.

GuoshouZ,ChengyeZ,ZhihuiL,etal.Effectsofhighdoseofanisodamineontherespiratoryfunctionofpatientswithtraumaticacutelunginjury.CellBiochemBiophys.2013Jun;66(2):365-9.PMID:23504631.

GengW,FuXH,GuXS,etal.Preventiveeffectsofanisodamineagainstcontrast-inducednephropathyintype2diabeticswithrenalinsufficiencyundergoingcoronaryangiographyorangioplasty.ChinMedJ(Engl).2012Oct;125(19):3368-72.PMID:23044290.

ZhangZX,WangP,ZhangQS,etal.Effectsofanisodamineontheexpressionsofvascularendothelialgrowthfactorandintercellularadhesionmolecule1inexperimentalinfusionphlebitis.ChinMedJ(Engl).2012Jan;125(2):300-5.PMID:22340563.

ZhangWW,SongMK,CuiYY,etal.Differentialneuropsychopharmacologicalinfluencesofnaturallyoccurringtropanealkaloidsanisodamineversusscopolamine.NeurosciLett.2008Oct10;443(3):241-5.PMID:18672024.

VarmaDR,YueTL.Adrenoceptorblockingpropertiesofatropine-likeagentsanisodamineandanisodineonbrainandcardiovasculartissuesofrats.BrJPharmacol.1986Mar;87(3):587-94.PMID:2879586.

品牌介绍

LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供：癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的，为全球提供先端的药物研发试剂、试剂盒、委托合成，并为药物生产企业提供原料，最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。试剂