LKT/ASIATICOSIDE/A7333/1 mg-免疫在线蚂蚁淘旗下平台

商品详细LKT/ASIATICOSIDE/A7333/1 mg

LKT/ASIATICOSIDE/A7333/1 mg

商品编号： A7333-1mg

品牌： lktlabs

市场价： ¥660.00

美元价： 396.00

产地：美国(厂家直采)

公司：

产品分类：临床研究

公司分类： clinical_research

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

ProductIDA7333

CasNo.16830-15-2

Purity≥90%

Description
ProductInfo
ShippingandStorage
Downloads
References

Description

AsiaticosideisatriterpenefoundinCentellathatexhibitsanti-inflammatory,neuroprotective,cognitionenhancing,antipyretic,antioxidative,pro-angiogenic,anticancerchemotherapeutic,andchemopreventiveactivities.AsiaticosideinhibitsmelanogenesisbydecreasingDNAbindingbyMITF;asaresult,itisoccasionallyusedinskinwhiteningtreatments.Asiaticosideinducesapoptosis,increasesactivationofcaspase3,decreasesreleaseofTNF-αandIL-1β,andsuppressestumordevelopmentandsizeinanimalmodelsofbreastcancer.Inanimalmodelsofcerebralischemia/reperfusion,asiaticosideimprovesmemoryandlearningdeficitsanddecreaseslevelsofIL-6,TNF-α,andIL-1β.Additionally,asiaticosidedecreasesLPS-inducedinflammationandfever,suppressesactivityofmyeloperoxidase,andincreasesactivityofhemeoxygenase1(HO-1)invivo.Thiscompoundalsosupportswoundhealingactivity,increasingcellmigration,attachment,andgrowthinvitro.

ProductInfo

CasNo.	16830-15-2
Purity	≥90%
Formula	C₄₈H₇₈O₁₉
FormulaWt.	959.12
ChemicalName	(2α,3β,4α)-2,3,23-Trihydroxyurs-12-en-28-oicacidO-6-deoxy-a-L-mannopyranosyl-(1->4)-O-β-D-glucopyranosyl-(1->6)-O-β-D-glucopyranosylester
IUPACName	[6-[[3,4-dihydroxy-6-(hydroxymethyl)-5-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxyoxan-2-yl]oxymethyl]-3,4,5-trihydroxyoxan-2-yl]10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylate
MeltingPoint	230-233°C
Solubility	Solubleinpropyleneglycolorethanol.
Appearance	WhiteCrystalPowder

ShippingandStorage

StoreTemp	4°C
ShipTemp	Ambient

Downloads

MSDS	A7333MSDSPDF
InfoSheet	A7333InfoSheetPDF

References

KwonKJ,BaeS,KimK,etal.Asiaticoside,acomponentofCentellaasiatica,inhibitsmelanogenesisinB16F10mousemelanoma.MolMedRep.2014Jul;10(1):503-7.PMID:24756377.

ChenS,YinZJ,JiangC,etal.Asiaticosideattenuatesmemoryimpairmentinducedbytransientcerebralischemia-reperfusioninmicethroughanti-inflammatorymechanism.PharmacolBiochemBehav.2014Jul;122:7-15.PMID:24631487.

Al-SaeediFJ.Studyofthecytotoxicityofasiaticosideonratsandtumourcells.BMCCancer.2014Mar25;14:220.PMID:24667059.

WanJ,GongX,JiangR,etal.Antipyreticandanti-inflammatoryeffectsofasiaticosideinlipopolysaccharide-treatedratthroughup-regulationofhemeoxygenase-1.PhytotherRes.2013Aug;27(8):1136-42.PMID:22972613.

LeeJH,KimHL,LeeMH,etal.Asiaticosideenhancesnormalhumanskincellmigration,attachmentandgrowthinvitrowoundhealingmodel.Phytomedicine.2012Oct15;19(13):1223-7.PMID:22939261.

品牌介绍

LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供：癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的，为全球提供先端的药物研发试剂、试剂盒、委托合成，并为药物生产企业提供原料，最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。试剂