Description
Bis(aziridinyl)methylaminophosphine is an anti-fertility/sterilization agent used to sterilize male insects and lamprey eels. This compound induces DNA fragmentation in spermatozoa and is very hazardous.
Bis(aziridinyl)methylaminophosphine is an anti-fertility/sterilization agent used to sterilize male insects and lamprey eels. This compound induces DNA fragmentation in spermatozoa and is very hazardous.
Cas No. | 13687-09-7 |
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Purity | ≥98% |
Formula | C5H12N3PS |
Formula Wt. | 177.21 |
Chemical Name | Bis(aziridinyl)methylamino phosphine sulfide |
IUPAC Name | P,P-Bis(1-aziridinyl)-N-methylphosphinothioic amide |
Synonym | Bisazir |
Melting Point | 69-72°C |
Solubility | Soluble in DMSO. |
Appearance | White to off white powder |
Store Temp | -20°C |
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Ship Temp | Dry Ice |
MSDS | B3373 MSDS PDF |
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Info Sheet | B3373 Info Sheet PDF |
Ciereszko A, Wolfe TD, Dabrowski K. Analysis of DNA damage in sea lamprey (Petromyzon marinus) spermatozoa by UV, hydrogen peroxide, and the toxicant bisazir. Theriogenology. Aquat Toxicol. 2005 Jun 15;73(2):128-38. PMID: 15885821.
Ciereszko A, Babiak I, Dabrowski K. Efficacy of animal anti-fertility compounds against sea lamprey (Petromyzon marinus) spermatozoa. Theriogenology. 2004 Apr 15;61(6):1039-50. PMID: 15036993.
Srivastava VK, Kumar K. Effect of the chemosterilant bisazir on the testes of the spotted bollworm Earias fabia stoll. Toxicology. 1984 Jun;31(3-4):335-42. PMID: 6740707.