LKT/TANSHINONE I/T0153/100 mg-免疫在线蚂蚁淘旗下平台

商品详细LKT/TANSHINONE I/T0153/100 mg

LKT/TANSHINONE I/T0153/100 mg

商品编号： T0153-100mg

品牌： lktlabs

市场价： ¥14380.00

美元价： 8628.00

产地：美国(厂家直采)

公司：

产品分类：临床研究

公司分类： clinical_research

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

立即询价

商品介绍

ProductIDT0153

CasNo.568-73-0

Purity≥95%

Description
ProductInfo
ShippingandStorage
Downloads
References

Description

TanshinoneIisaditerpenefoundinSalviathatexhibitsneuroprotective,anti-inflammatory,antioxidative,anti-angiogenic,anticancerchemotherapeutic,andchemopreventiveactivities.TanshinoneIupregulatesexpressionofIL-4andIL-13,protectingagainstcerebralischemia/reperfusion-inducedinjuryinvivo.TanshinoneIalsodecreasesperoxynitrite-inducedDNAdamageandrADIcalformation.Additionally,tanshinoneIinhibitsexpressionofVEGF,cyclinA,cyclinB,andAurAinvariousmodelsoflungcancer,inhibitingcellularandtumorgrowth.

ProductInfo

CasNo.	568-73-0
Purity	≥95%
Formula	C₁₈H₁₂O₃
FormulaWt.	276.29
ChemicalName	1,6-Dimethylphenanthro(1,2-b)furan-10,11-dione
IUPACName	1,6-dimethylnaphtho[1,2-g][1]benzofuran-10,11-dione
Synonym	TanshinoneA
MeltingPoint	233-234°C
Solubility	SolubleinDMSO.
Appearance	Darkpurplecrystal

ShippingandStorage

StoreTemp	4°C
ShipTemp	Ambient

Downloads

MSDS	T0153MSDSPDF
InfoSheet	T0153InfoSheetPDF

References

ParkJH,ParkOK,ChoJH,etal.Anti-inflammatoryEffectofTanshinoneIinNeuroprotectionAgainstCerebralIschemia-ReperfusionInjuryintheGerbilHippocampus.NeuRochemRes.2014Apr24.[Epubaheadofprint].PMID:24760430.

ZhouS,ChenW,SuH,etal.ProtectivepropertiesoftanshinoneIagainstoxidativeDNAdamageandcytotoxicity.FoodChemToxicol.2013Dec;62:407-12.PMID:24021569.

TungYT,ChenHL,LeeCY,etal.ActiveComponentofDanshen(SalviamiltiorrhizaBunge),TanshinoneI,AttenuatesLungTumOrigenesisviaInhibitionsofVEGF,CyclinA,andCyclinBExpressions.EvidBasedComplementAlternatMed.2013;2013:319247.PMID:23662128.

TaoS,ZhengY,LauA,etal.TanshinoneIactivatestheNrf2-dependentantioxidantresponseandprotectsagainstAs(III)-inducedlunginflammationinvitroandinvivo.AntioxidRedoxSignal.2013Nov10;19(14):1647-61.PMID:23394605.

LiY,GongY,LiL,etal.BioactivetanshinoneIinhibitsthegrowthoflungcancerinpartviadownregulationofAuroraAfunction.MolCarcinog.2013Jul;52(7):535-43.PMID:22389266.

LiW,LiJ,AshokM,etal.Acardiovasculardrugrescuesmicefromlethalsepsisbyselectivelyattentuatingalate-actingproinflammatorymediator,highmobilitygroupbox1.JImmunol.2007Mar15;178(6):3856-3864.PMID:17339485.

ZhangY,WonSH,JiangC,etal.TanshinonesfmorChinesemedicinalherbDanshen(SalviamiltiorrhizaBunge)suppressprostatecancergrowthandandrogenreceptorsignaling.PharmRes.2012Jun;29(6):1595-1608.PMID:22281759.

品牌介绍

LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供：癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的，为全球提供先端的药物研发试剂、试剂盒、委托合成，并为药物生产企业提供原料，最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。试剂