Theophyllineisamethylxanthinecompoundthatexhibitsbronchodilatory,anti-asthma,anti-tussive,andanti-inflammatoryactivities.Theophyllineisclinicallyusedtotreatrespiratorydiseasessuchaschronicobstructivepulmonarydisorder(COPD),asthma,andcough.Theophyllineisanonselectiveinhibitorofphosphodiesterases(PDEs),increasingcAMPlevelsandPKAactivation;italsoinhibitsadenosineA1/2receptors.
| CasNo. | 58-55-9 |
|---|---|
| Purity | ≥98% |
| Formula | C7H8N4O2 |
| FormulaWt. | 180.16 |
| ChemicalName | 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione |
| IUPACName | 1,3-dimethyl-7H-purine-2,6-dione |
| Synonym | Theophyllineanhydrous;1,3-Dimethylxanthine;Diphyllin;Elixicon;Sustaire |
| MeltingPoint | 271-273°C |
| Solubility | Slightlysolubleinwater. |
| Appearance | WhiteCrystalPowder |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| InfoSheet | T2817InfoSheetPDF |
|---|
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DalyJW,JacobsonKA,UkenaD.Adenosinereceptors:developmentofselectiveagoNISTsandantagonists.ProgClinBiolRes.1987;230:41-63.PMID:3588607.
