Diphenhydramineisafirstgenerationantihistaminethatexhibitsanti-tussive,antiemetic,sedative,anti-allergic,andanticholinergicactivities.Diphenhydramineinhibitsmuscarinicacetylcholinereceptors(mAChRs)andNa+channelsandactsasaninverseagoNISTathistamineH1receptors.Invivo,diphenhydraminedecreasesleukocyteinfiltrationintoinjurysites.
| CasNo. | 147-24-0 |
|---|---|
| Purity | ≥98% |
| Formula | C17H21NO•HCl |
| FormulaWt. | 291.82 |
| ChemicalName | 2-Diphenylmethoxy-N,N-dimthylethanaminehydrochloride |
| IUPACName | 2-benzhydryloxy-N,N-dimethylethanamine;hydrochloride |
| Synonym | Alledryl;Amidryl;Benadryl;Dihydral;Dolestan;Halbmond;Noctomin;Syntedril |
| MeltingPoint | 166-170°C |
| Solubility | Solubleinacetone(20mg/mL),water(1g/mL),andalcohol(500mg/mL).Slightlysolubleinbenzeneorether. |
| Appearance | Whitecrystallinepowder |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| MSDS | D3462MSDSPDF |
|---|---|
| InfoSheet | D3462InfoSheetPDF |
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